Malondialdehyde belong to the class of β-dicarbonyls. A colorless liquid, malondialdehyde is a highly reactive compound that occurs as the enol. [2] . It is a physiological metabolite, and a marker for oxidative stress. Malondialdehyde mainly exists as its enol, hydroxyacrolein: [2]

丙二醛(MDA)是常用的膜脂过氧化指标，在较高温度（95度）及酸性环境中可与硫代巴比妥酸(thiobarbituric acid，TBA)缩合，形成红色的MDA-TBA加合物，相应的反应原理图，如下：

2017年5月1日 · Under acidic conditions (e.g., glacial acetic acid or sulfuric acid) and elevated temperatures (e.g., 95 °C) for extended reaction time (e.g., 60 min), one molecule of MDA reacts with two molecules of TBA to form a red-coloured, strongly visible light-absorbing (λ max, 532 nm) and fluorescent (λ ex, 515 nm; λ em, 553 nm) derivative or TBA ...

Malondialdehyde (MDA) is one of several low-molecular-weight end products formed via the decomposition of certain primary and secondary lipid peroxidation products. At low pH and elevated temperature, MDA readily participates in nucleophilic addition reaction with 2-thiobarbituric acid (TBA), generating a red, fluorescent 1:2 MDA:TBA adduct.

2016年10月15日 · 碧云天的脂质氧化(MDA)检测试剂盒(Lipid Peroxidation MDA Assay Kit)采用一种基于MDA和硫代巴比妥酸(thiobarbituric acid,TBA)反应产生红色产物的显色反应，随后通过比色法用于对血浆、血清、尿液、动植物组织或细胞裂解液中MDA进行定量检测，广泛

2022年10月1日 · Malondialdehyde (MDA) is an endogenous genotoxic product of lipid peroxidation and its accumulation in the human body is associated with various diseases. To accurately understand the role of MDA in physiological and pathological processes, it is of great significance to develop a robust and reliable method for rapid detection of MDA.

Malondialdehyde (MDA) is one of the final products of polyunsaturated fatty acids peroxidation in the cells. An increase in free radicals causes overproduction of MDA. Malondialdehyde level is commonly known as a marker of oxidative stress and the antioxidant status in cancerous patients.

2017年5月1日 · Malondialdehyde (MDA), 4-hydroxy-nonenal (HNE) and the F 2-isoprostane 15(S)-8-iso-prostaglandin F 2α (15(S)-8-iso-PGF 2α) are the best investigated products of lipid peroxidation.

2021年9月30日 · Lipids are very sensitive to oxidant attack and to-date, malondialdehyde (MDA), 4-hydroxy-2-nonenal (4-HNE) and F2-isoprostane are the main biomarkers for lipid peroxidation assessment. They all derive from polyunsaturated fatty acids (PUFAs) either by enzyme-catalyzed reactions (physiological) or by non-enzyme reactions (pathological).

丙二醛（mda）是脂质过氧化作用下的代表性终产物之一，指示食品中脂质氧化的程度。 然而，腌制品中的化合物，特别是咸瘦猪肉中的亚硝酸盐在酸性条件下会与MDA反应，导致MDA的损失和常规检测对脂质氧化的低估。