1998年7月1日 · The actinomycin D chase experiment revealed that ET-1 did not alter the stability of VEGF mRNA (Figure 5C), suggesting that ET-1 regulated VEGF mRNA expression by the …

2013年3月18日 · The increased amount of VEGF-A mRNA observed in ASP13 transfectants was not associated with differences in mRNA stability, measured when actinomycin D was added …

2024年1月5日 · V5-3 can accurately target and neutralize the two key targets of VEGF and TNF-α in RA. V5-3 effectively inhibits joint inflammation in CIA mice. V5-3 significantly inhibits the …

2005年5月9日 · Both IL-1β and TGFβ increased VEGF-A 165 mRNA and VEGF promoter luciferase construct activity, in addition VEGF-A protein was inhibited by actinomycin D …

Vascular endothelial growth factor (VEGF)-D is a lymphangiogeneic and angiogeneic growth factor that signals through receptors on the surface of endothelial cells. Here, we demonstrate …

2020年9月29日 · The mRNA stability and degradation halftime of VEGF in HCT116 and RKO treated by Actinomycin D. f. Knockdown of IGF2BP3 repressed concentration of secreted …

2000年9月9日 · Inhibition of cellular transcription with actinomycin D after treatment with 100 nM E 2 for 15 h resulted in substantial decay of VEGF mRNA (Fig. (Fig.2), 2), suggesting that E 2 …

The effect of atRA was dose-dependent in a range between 10(-7) M and 10(-6) M. Treatment with actinomycin D revealed that atRA induces the VEGF gene at the transcriptional level. Of …

2017年10月13日 · Vascular endothelial growth factor (VEGF) is a key regulator of developmental, physiological, and tumor angiogenesis. Upregulation of VEGF expression by hypoxia appears …

2001年7月5日 · Actinomycin D (5 μg/ml) was added to the culture to block further gene transcription; the mRNA was isolated 0, 1, 2, 4, 8 and 16 h after the addition of actinomycin D. …