2024年12月24日 · ADAM23 (ADAM Metallopeptidase Domain 23) is a Protein Coding gene. Diseases associated with ADAM23 include Epilepsy, Familial Temporal Lobe, 1 and …

Disintegrin and metalloproteinase domain-containing protein 23 is a non-catalytic protein that in humans is encoded by the ADAM23 gene. [5] [6] It is a member of the ADAM family of …

ADAM23 regulates neuronal differentiation by triggering specific signaling pathways during human neural progenitor cells differentiation. High ADAM23 gene methylation is associated with …

2017年8月18日 · In this study, we showed that ADAM23 contributes to cell survival and is involved in neuronal differentiation during the differentiation of human neural progenitor cells …

2014年3月24日 · Here, we show that invasive breast tumors exhibit significant ADAM23-ITH and that this heterogeneity is critical for tumor growth and metastasis. We demonstrate that while …

2018年9月18日 · Cardiac-specific conditional ADAM23-knockout mice significantly exhibited exacerbated cardiac hypertrophy, fibrosis, and dysfunction, whereas transgenic mice …

2004年12月1日 · Using an antibody that we raised against the rat ADAM23 disintegrin domain, we found that ADAM23 is present at detectable levels only in nervous system tissue. Our analysis …

2024年1月23日 · Proteomic analysis using epitope-tagged Lgi3 knockin mice shows that LGI3 uses ADAM23 as a receptor and selectively co-assembles with Kv1 channels. A lack of Lgi3 in …

该基因编码 ADAM (一种去整合素和金属蛋白酶结构域) 家族的成员。 该家族的成员是膜锚定蛋白，在结构上与蛇毒解离蛋白相关，并参与涉及细胞-细胞和细胞-基质相互作用的各种生物过 …

2015年6月18日 · ADAM23 plays a role in synaptic transmission and interacts with known epilepsy genes, LGI1 and LGI2, and should be considered as a candidate gene for human epilepsies. …