Adenosine receptor - Wikipedia
The adenosine receptors (or P1 receptors [1]) are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand. [2] There are four known types of adenosine receptors in humans: A 1, A 2A, A 2B and A 3; each is encoded by a different gene.
Adenosine Receptors: Expression, Function and Regulation
Adenosine receptors (ARs) comprise a group of G protein-coupled receptors (GPCR) which mediate the physiological actions of adenosine. To date, four AR subtypes have been cloned and identified in different tissues.
Adenosine Receptors: Pharmacology, Structure–Activity ...
Adenosine receptors have been affinity labeled using agonist and antagonist probes, often containing high specific radioactivity, carrier-free iodine-125 to facilitate identification of the labeled receptor.
Adenosine Receptor - an overview | ScienceDirect Topics
An adenosine receptor is a type of GPCR (G-protein coupled receptor) that binds with adenosine, a naturally occurring molecule in the body. There are four types of adenosine receptors: A1, A2A, A2B, and A3.
Introduction to Adenosine Receptors as Therapeutic Targets
Adenosine acts as a cytoprotective modulator in response to stress to an organ or tissue. Although short-lived in the circulation, it can activate four sub-types of G protein-coupled adenosine receptors (ARs): A1, A2A, A2B, and A3. The ...
Adenosine receptors: what we know and what we are learning
Adenosine, beside its role in the intermediate metabolism, mediates its physiological functions by interacting with four receptor subtypes named A(1), A(2A), A(2B) and A(3). All these receptors belong to the superfamily of G protein-coupled receptors that …
Adenosine Receptors: Structure, Distribution, and Signal ...
2018年7月29日 · Adenosine receptors A1, A2A, A2B, and A3 are effector proteins triggered by the endogenous nucleoside adenosine to exert its numerous vital physiological effects, behaving like a guardian angel. This chapter offers an overview of the updated knowledge concerning the...