Adrenergic blocking agents treat certain diseases through blocking the adrenergic receptor, [2][3] preventing it from being activated by noradrenaline and epinephrine. As a result, it stops the body from producing the "fight-or-flight" responses.

2023年7月2日 · Beta-blockers may be used to treat adverse effects arising from adrenergic receptor agonists acutely. Beta-blockers can treat tachycardia and hypertension that may occur from vasopressors.

2022年9月18日 · consumption is decreased, and thereby decreases the heart rate and aortic pressure. • In blood vessels, these drugs reduces the noradrenaline release from the sympathetic terminals and decrease the renin from kidney due to the blockade of β receptors Classification: Adrenergic blocking agents I. Alpha receptor blocking agents: a. Beta halo ...

Adrenergic neurone blockers, commonly known as adrenergic antagonists, are a group of drugs that inhibit the sympathetic nervous system by blocking the activity of adrenergic neurones. They prevent the action or release of catecholamines such as norepinephrine and epinephrine.

Beta-blockers bind to beta-adrenoceptors in cardiac nodal tissue, the conducting system, and contracting myocytes. The heart has both β 1 and β 2 adrenoceptors, although the predominant receptor type in number and function is β 1. These receptors primarily bind norepinephrine that is released from sympathetic adrenergic nerves.

2003年5月13日 · Beta-adrenergic blockers (β-blockers) are an important class of drugs for the treatment of various heart diseases, including high blood pressure, insufficiency of blood flow to the heart muscle (angina pectoris), irregular heart beat (arrhythmias), thickened heart muscle (hypertrophic cardiomyopathy), and decreased ability of the heart to ...

Here we review the intracellular pathways of β-adrenergic action, the mechanisms of cellular and tissue level regulation of cardiac electrical activity and arrhythmia, and the evidence for clinical antiarrhythmic indications for β-blocker therapy in cardiac diseases and arrhythmias, such as atrial fibrillation (AF), myocardial infarction (MI ...

2022年9月12日 · Direct-acting, indirect-acting, and mixed-acting sympathomimetics are the three types of sympathomimetic drugs. Direct-acting sympathomimetic medications bind to one or more adrenergic receptors directly.

β‐Blockers are appropriate treatment for patients with hypertension and those who have concomitant ischemic heart disease, heart failure, obstructive cardiomyopathy, or certain arrhythmias. β‐Blockers can be used in combination with other antihypertensive drugs to achieve maximal blood pressure control.

Adrenergic blockers influence physiological responses by inhibiting the action of norepinephrine and epinephrine at adrenergic receptors. This inhibition results in decreased heart rate and blood pressure, as well as relaxation of smooth muscles.