2023年8月4日 · Inflammatory bowel disease (IBD) is characterized by repetitive episodes of inflammation of the gastrointestinal tract caused by an abnormal immune response to gut …

Environmental factors, genetic factors and immune responses have been considered as the major etiology of IBD. Despite the diversified pathogenesis of the disease, no guaranteed curative …

Although the etiology of IBD remains largely unknown, it involves a complex interaction between the genetic, environmental or microbial factors and the immune responses. Of the four …

Among the many puzzles of IBD pathogenesis, one of the less understood and most difficult to tackle is the role of environmental factors in the appearance and progression of CD and UC in …

In this review, we described the primary and adaptive immune system response in the gut and the known immune pathogenetic pathways leading to the development of IBD. We also described …

Adherent-invasive Escherichia coli appear specific to ileal Crohn’s disease and have been shown to induce the release of TNF-α, a key cytokine in IBD inflammation. The aim of this article is to …

A Aetiology of IBD: the onset of inflammatory bowel disease involves a significant interplay between genetic predisposition and environmental factors, with dysbiosis, an imbalanced state …

2019年12月20日 · The aetiology of IBD is not fully known, but it has been linked to genetic, immunological, and environmental factors playing a role in the development of the disease. …

2019年1月1日 · In this article, we will review the mechanisms proposed to cause IBD from the genetic, environmental, intestinal barrier, and immunologic perspectives.

In this review, we have systemically reviewed the pathogenesis of IBD and highlighted recent advances in host genetic factors, gut microbiota, and environmental factors and, especially, in …