
Argonaute 2蛋白(AGO2)是什么? - 知乎专栏
2024年7月30日 · Argonaute 2蛋白(AGO2),亦称真核翻译起始因子2C2 ( eukaryotic translation initiation factor 2C subunit 2,EIF2C2) 。 含有N末端( amino-terminal) 、PAZ、MID 和PIWI 四 …
Germline AGO2 mutations impair RNA interference and human
2020年11月16日 · We identify 13 heterozygous mutations in AGO2 in 21 patients affected by disturbances in neurological development. Each of the identified single amino acid mutations …
Structural Dynamics of Human Argonaute2 and Its Interaction with …
The human Argonaute2 protein (Ago2) is a key player in RNA interference pathway and small RNA recognition by Ago2 is the crucial step in siRNA mediated gene silencing mechanism. …
ago2蛋白有什么用? - 华美生物
2023年10月16日 · AGO2(Argonaute 2)蛋白是RNA干扰(RNAi)和微小RNA(miRNA)通路中的一种关键因子,具有重要的生物学功能。 具体来说,AGO2蛋白可与小RNA(如siRNA …
RNA干扰(二)——船蛸 - 知乎 - 知乎专栏
目前也发现了Ago2与常染色质中启动常规mRNA转录的RNAP II发生互作、控制活性,在Ago1也发现了类似的作用。Ago2还以非RNAi依赖的方式与绝缘子的功能相关。这些非常规功能在此仅 …
AGO2 silences mobile transposons in the nucleus of quiescent …
2023年11月20日 · Argonaute 2 (AGO2) is a cytoplasmic component of the miRNA pathway, with essential roles in development and disease. Yet little is known about its regulation in vivo. …
mRNA structural dynamics shape Argonaute-target interactions
2020年7月13日 · Our results uncover how dynamic changes in mRNA structure shape AGO2-target recognition, provide estimates of mRNA folding and unfolding rates in vivo, and provide …
超有特色的AGO2抗体 - 知乎 - 知乎专栏
Argonaute2蛋白 (AGO2)通过参与构成 RNA诱导的沉默复合体,其自身催化及自身过表达功能,在人类肿瘤的发生发展中扮演了重要角色,逐渐成为研究焦点。 Ago2表达水平变化或功能失调 …
Germline AGO2 mutations impair RNA interference and human
2020年11月16日 · We identify 13 heterozygous mutations in AGO2 in 21 patients affected by disturbances in neurological development. Each of the identified single amino acid mutations …
The RNA Interference Effector Protein Argonaute 2 Functions as a ...
Argonaute 2 (Ago2) is a key component of the RNA interference (RNAi) pathway, a gene-regulatory system that is present in most eukaryotes. Ago2 uses microRNAs (miRNAs) and …