2024年12月24日 · AGPAT1 (1-Acylglycerol-3-Phosphate O-Acyltransferase 1) is a Protein Coding gene. Diseases associated with AGPAT1 include Complete Generalized Lipodystrophy and …

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha is an enzyme that in humans is encoded by the AGPAT1 gene. [5] [6] [7] This gene encodes an enzyme that converts lysophosphatidic …

磷脂酸磷酸酶（PAP1）可除去磷脂酸的磷酸基，得到1,2- 二酰基甘油 （DAG）。 DAG与脂酰辅酶A生成甘油三酯（TAG），由二酰基甘油O-酰基转移酶（DGAT）催化。 人类有两种同工酶， …

该基因编码一种将溶血磷脂酸 (LPA) 转化为磷脂酸 (PA) 的酶。 LPA 和 PA 是参与信号转导和细胞脂质生物合成的两种磷脂。 该酶定位于内质网。 该基因位于人类主要组织相容性复合体的 III …

2024年12月10日 · AGPAT1 as a Novel Colonic Biomarker for Discriminating Between Ulcerative Colitis With and Without Primary Sclerosing Cholangitis. Vessby J, Wisniewski JR, Lindskog …

2025年2月8日 · Gene ID: 10554, updated on 8-Feb-2025. This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two …

Baculovirus-mediated AGPAT1 overexpression indicates a preference for fatty acid species C12–16:0, C16:1, C18:2, and C18:3, followed by C18:0, C18:1, and C20:4, and poor activity …

AGPAT1 exhibited acyl acceptor specificity for LPA with the absence of activity for other lysophospholipids, but showed broad acyl donor specificity for acyl-CoA with a preference for …

2025年2月8日 · The Agpat1-deficient mouse provides an important model in which to study the contribution of phospholipid and triacylglycerol synthesis to physiology and diseases. …

AGPAT1基因：一个关键的脂肪代谢调节者. AGPAT1基因，全名为1-acylglycerol-3-phosphate O-acyltransferase 1，位于人类染色体6p21.32上。这个基因编码的蛋白质在脂肪代谢过程中扮演 …