Functional and Pathological Roles of AHCY - PMC
Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved proteins in living organisms. AHCY catalyzes the reversible break of S -adenosylhomocysteine (SAH), the …
AHCY Gene - GeneCards | SAHH Protein | SAHH Antibody
2024年12月24日 · AHCY (Adenosylhomocysteinase) is a Protein Coding gene. Diseases associated with AHCY include Hypermethioninemia With S-Adenosylhomocysteine Hydrolase …
复旦大学附属肿瘤医院雷群英教授团队在SAH作为信号分子通过AH…
2021年6月7日 · 在高等生物中腺苷高半胱氨酸酶AHCY ( adenosylhomocysteinase) 是唯一分解SAH的酶，因此抑制 AHCY的酶活导致细胞内SAH的积累，进而抑制甲基转移反应，AHCY的 …
AHCY Gene: Tying together methylation and homocysteine
2024年5月29日 · AHCY is the gene that encodes the enzyme adenosylhomocysteinase. In mammals, AHCY is the only enzyme that can convert SAH to homocysteine, and it can also …
腺苷同型半胱氨酸酶（AHCY）基因 | MCE - MCE-生物活性 ...
它催化 S-腺苷高半胱氨酸 (AdoHcy) 可逆水解为腺苷 (Ado) 和 L-高半胱氨酸 (Hcy) 。 因此，它调节细胞内 S-腺苷高半胱氨酸 (SAH) 浓度，该浓度被认为对转甲基反应很重要。 这种蛋白质的缺 …
生科院易文课题组在PNAS发表论文揭示蛋白糖基化调控干细胞多 …
2020年4月23日 · 腺苷同型半胱氨酸水解酶（ Adenosylhomocysteinase, AHCY ）是甲硫氨酸代谢途径中重要的代谢酶，它催化 硫代 腺苷同型半胱氨酸（ S-adenosylhomocysteine, SAH ）水 …
Functional and Pathological Roles of AHCY - ResearchGate
2021年3月31日 · Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved proteins in living organisms. AHCY catalyzes the reversible break of S...
雷群英团队《Autophagy》报道AHCYL1可作为代谢物SAH的感受器
由于SAM和SAH都不能自由穿越细胞膜，通过SAM合酶的抑制剂cLEU和AHCY的抑制剂ADOX分别降低胞内SAM的浓度和积累SAH。 和之前的报道一致，减少SAM能够通过抑制MTOR激活自 …
Human S-adenosylhomocysteine hydrolase: common gene …
S-Adenosylhomocysteine hydrolase (AHCY) is the only mammalian enzyme known to catalyze the hydrolysis of S-adenosylhomocysteine. We have used a genotype-to-phenotype strategy …
Functional and Pathological Roles of AHCY - Frontiers
2021年3月30日 · Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved proteins in living organisms. AHCY catalyzes the reversible break of S …