2024年11月2日 · Gene target information for bru3 - bruno 3 (fruit fly). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

bruno 3 (bru3) encodes an RNA binding protein that binds to the EDEN element and mediates maternal mRNA translational repression. [Date last reviewed: 2019-09-19]

Drosophila melanogaster (fruit fly) Enables RNA binding activity and protein homodimerization activity. Predicted to be involved in mRNA splice site recognition; negative regulation of …

Gene ID: 39527, updated on 8-Feb-2025. Enables RNA binding activity and protein homodimerization activity. Predicted to be involved in mRNA splice site recognition; negative …

2018年5月21日 · Bru-3 displays predominantly cytoplasmic expression in muscles and its muscle-specific overexpression causes a range of phenotypes also observed in the fly DM1 model, …

Sequence and secondary structure analysis of the Bru-3 linker region. ( A ) Sequence comparison of the linker region of the Bruno-like proteins analysed in this work. The MEME program …

Intron length and alternative splicing of Bru-3 in distantly related Drosophila species. (A) Splice choices identified in D. melanogaster, D. pseudoobscura, D. persimilis and D. virilis. Only ...

We show in the present work that the Drosophila Bruno paralogue, the 45 kDa Bru-3 protein (p45), binds specifically to the EDEN element and acts as a homodimer. We describe for the …

Here, we show that Drosophila CELF1 family member Bru-3, contributes to pathogenic musc... ... assess the functionality of muscles with increased Bru-3 levels, we performed a righting assay …

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