2024年12月24日 · AKAP1 (A-Kinase Anchoring Protein 1) is a Protein Coding gene. Diseases associated with AKAP1 include Prostate Cancer and Long Qt Syndrome 8. Among its related pathways are Activation of cAMP-Dependent PKA and ADORA2B mediated anti-inflammatory cytokines production.

This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [7]

2004年12月1日 · Here, we discuss two emerging principles in AKAP signalling: the combinatorial assembly of different enzymes on the same AKAP backbone; and the dynamic reorganization of AKAP complexes. cAMP...

2024年5月5日 · This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

AKAPs are a diverse group of molecules that function as cell signaling scaffolds. Specifically, AKAPs dynamically organize and juxtapose protein kinase A (PKA) with specific substrates and other signaling machinery at specific cellular locales.

2024年12月24日 · AKAP9 (A-Kinase Anchoring Protein 9) is a Protein Coding gene. Diseases associated with AKAP9 include Long Qt Syndrome 11 and Long Qt Syndrome 1. Among its related pathways are Loss of proteins required for interphase microtubule organization from the centrosome and Activation of cAMP-Dependent PKA.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene …

2024年12月24日 · AKAP12 (A-Kinase Anchoring Protein 12) is a Protein Coding gene. Diseases associated with AKAP12 include Spermatogenic Failure 19 and Long Qt Syndrome 8. Among its related pathways are Activation of cAMP-Dependent PKA and Signaling by Rho GTPases.

Gene ID: 11214, updated on 9-Feb-2025. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family.

2022年4月11日 · Combining gene-level results with SCHEMA, AKAP11 emerges as a definitive risk gene (odds ratio (OR) = 7.06, P = 2.83 × 10 −9). At the protein level, AKAP-11 interacts with GSK3B, the...