2023年11月25日 · Acute kidney injury (AKI), previously called acute renal failure (ARF), denotes a sudden and often reversible reduction in kidney function, as measured by glomerular filtration rate (GFR).

Acute kidney injury is a clinical syndrome characterized by a rapid decline in glomerular filtration rate and resultant accumulation of metabolic waste products....

AKI患者全因死亡的危险因素包括：心血管手术史、重症监护、较高的AKI分期、基础CKD、基线eGFR<30 ml·min -1 ·（1.73 m 2） -1 、大量蛋白尿等，最常见的死亡原因是心血管疾病和恶性肿瘤（2C）。

Radioactive GFR markers, such as 39 Cr-EDTA and 99mTc-DTPA (99m-Technetium diethylene triamine pentaacetate) have been used in conjunction with a radiation detector to monitor GFR in patients with AKI at rates close to real-time. 40, 41 The measured plasma clearance showed excellent correlations with GFRs simultaneously measured using the ...

2023年3月16日 · Most cases of AKI will resolve without specific intervention (e.g., with treatment of underlying sepsis). However, occasionally, a specific issue is identified which requires particular therapy (e.g., Foley catheter obstruction, glomerulonephritis).

2024年10月16日 · The evidence for the prognostic accuracy of estimated glomerular filtration rate (eGFR) for iodine-based contrast media-associated acute kidney injury showed that a lower eGFR is associated with an increased risk of acute kidney injury.

Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated with high mortality rates. The primary causes of AKI include ischemia, hypoxia or nephrotoxicity. An underlying feature is a rapid decline in GFR usually associated with decreases in renal blood flow.

1 天前 · Acute kidney injury (AKI) refers to the sudden damage to the renal parenchyma or sharp decline in kidney function, resulting from a range of factors with diverse underlying mechanisms. AKI can be broadly categorized into pre-renal AKI, which is centered on decreased glomerular filtration rate (GFR) due to decreased renal perfusion, and post-renal AKI, which is …

2015年5月30日 · 急性肾损伤（acute kidney injury，AKI）以往称为急性肾衰竭（acute renal failure，ARF），是指由多种病因引起的肾功能快速下降而出现的临床综合征。 可发生于既往无肾脏病者，也可发生在原有慢性肾脏病的基础上。 与 ARF 相比，AKI 的提出更强调对这一综合征早期诊断、早期治疗的重要性。 约 5% 住院患者可发生 AKI，在重症监护室（ICU）其发生率高达 30%，尽管肾病学界对 AKI 日趋重视，但目前仍无特异治疗，死亡率高，是肾脏病中的急危重 …

2013年6月15日 · Estimation of kidney function in critically ill patients with acute kidney injury (AKI), is important for appropriate dosing of drugs and adjustment of therapeutic strategies, but challenging due to fluctuations in kidney function, creatinine metabolism and fluid balance.