研究显示感染性休克患者在完成早期目标导向治疗（EGDT）并不能降低AKI的发生率，维持中心静脉血氧饱和度（ScvO 2 ）≥70%、MAP≥65 mmHg仍有46%的患者发生AKI [46] 。

2023年11月19日 · Chronic kidney disease (CKD) is divided into five stages, ranging from stage 1 to stage 5. Each stage is determined by a blood test known as the estimated glomerular filtration rate (eGFR), which establishes how well your kidneys filter waste and …

2019年12月1日 · Prerenal acute kidney injury is associated with decreased renal perfusion and glomerular filtration rate (GFR) caused by intravascular volume depletion secondary to...

In summary, the rapid and accurate measurement of GFR in AKI is important for diagnosis, severity of injury stratification, and potential therapeutic purposes. Rapid identification and determination of the extent of AKI will allow for early treatment, including dialysis initiation, as well as enrollment and stratification in clinical studies.

2023年11月25日 · Acute kidney injury (AKI), previously called acute renal failure (ARF), denotes a sudden and often reversible reduction in kidney function, as measured by glomerular filtration rate (GFR).[1][2][3] However, immediately after a renal insult, blood urea nitrogen (BUN) or creatinine (Cr) levels may be within the normal range, and the only sign of ...

Acute renal failure is defined as a rapid decrease in the glomerular filtration rate (gfr), occurring over a period of hours to days. This leads to an increase in serum concentration of nitrogenous excretory products and creatinine leading to the inability of the kidney to regulate electrolyte and fluid homeostasis appropriately.

In the present study on critically ill patients with early AKI, the performance of urinary CrCl and various estimation equations for assessment of GFR were compared to one of the gold standard techniques for measurement of GFR, the 51 Cr-EDTA infusion clearance technique. The main findings were that urinary CrCl, which has been used as a ...

2023年11月25日 · Acute kidney injury (AKI), formerly known as acute renal failure (ARF), denotes a sudden and often reversible reduction in kidney function, as measured by glomerular filtration rate (GFR). [1] [2] [3] There is no clear definition of AKI.

Our study shows that calculating GFR using kGFR formula instead of CKD-EPI may change drug dosages among patients with AKI admitted in ICU. By replacing conventional GFR estimation formulas with kGFR we may reduce the drug dosing inaccuracies that are currently prevalent in this cohort of patients.

2020年11月1日 · The objective of our study was to assess the performance of the kinetic estimated GFR (KeGFR) and Jelliffe equations to estimate GFR in AKI, using a radioisotopic method (technetium-diethylenetriaminepentaacetic acid) as a reference measure.