2025年1月20日 · Herein, we develop an efficient and practical method for synthesizing (E)-allyl ethers from readily available internal alkenes and alcohols or phenols via selective allylic C–H oxidation.

2014年3月5日 · A strategy for the allylic oxidation of cyclic alkenes with a copper–aluminum mixed oxide as catalyst is presented. The reaction involves the treatment of an alkene with a carboxylic acid employing tert -butyl hydroperoxide as the oxidant. In all cases, the corresponding allylic esters are obtained.

Biocatalytic C–H oxyfunctionalization to synthesize allylic oxidized products has attracted great attention in recent years, with the ability to simplify synthetic approaches toward complex compounds. As a result, scientists have found some new enzymes and mutants through techniques of gene mining and enzyme-directed evolution in recent years.

Allylic substitution, pioneered by the work of Tsuji and Trost, has been an invaluable tool in the synthesis of complex molecules for decades. An attractive alternative to allylic substitution is the direct functionalization of allylic C–H bonds of unactivated …

2025年2月1日 · Herein, we report the selective allylic C–H oxidation of cycloolefins to allylic alcohols via a PEC approach using BiVO 4 -based photoanode (Fig. 1 c). Specifically, cyclohexene can be converted to 2-cyclohexenol over BiVO 4 photoanode with a high selectivity of 96.4 % and a productivity of 1.74 μmol cm –2 h –1 under alkaline aqueous ...

2024年8月12日 · Herein, we disclose a simple copper-catalyzed method for enantioselective allylic C (sp 3)−H oxidation of unsymmetrical acyclic alkenes, specifically 1-aryl-2-alkyl alkenes. The C−H substrates are used in limiting amounts, and the products are obtained with high enantioselectivity, E / Z -selectivity, and regioselectivity.

2017年6月21日 · Here we report the enantioselective, regioselective and E/Z-selective allylic oxidation of unactivated internal alkenes via a catalytic hetero-ene reaction with a chalcogen-based oxidant.

2024年1月19日 · Allylic C–H bond oxidation of alkenes serves as possibly the most employed C–H bond functionalization reaction. However, sustainable and selective approaches remain scarce, and the majority of the existing conditions still …

2025年4月7日 · A general, efficient and economic copper-catalyzed α, β-enones allylic oxidation to 1,4-enedione has been developed. The protocol only requires a small amount of cheap copper catalyst with air as the...

2025年3月13日 · The resulting allylic or propargylic radical was expected to engage in radical recombination with the chiral Cu (II) center in close proximity, facilitating C–O bond formation through an inner sphere pathway. This mechanism is poised to improve enantioselectivity in the asymmetric C (sp 3)–H oxidation.