Know comprehensive Alkaline Phosphatase/ALPL protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.

Alkaline phosphatases are specific enzymes present in nearly all living organisms catalyzing the dephosphorylation of pyrophosphate (PPi) and pyridoxal-5′-phosphate (PLP) in vivo, …

此外，ALPL 主要通过调节无机磷酸盐 (Pi) 和无机焦磷酸盐 (PPi) 之间的平衡来刺激矿化，并在心血管重塑中发挥作用。 Alkaline Phosphatase /ALPL Protein, Mouse (HEK293, His) 是重组的 …

2024年7月16日 · The ALPL gene variant database is an open-access archive for interpretation of the clinical significance of variants reported in ALPL. The database contains coding and non …

In humans, the ALPI, ALPP, ALPPL2 and ALPL genes encode intestinal (IALP), placental (PALP), tissue-specific germ cell (GCALP) and non-tissue-specific (TNSALP) ALP isoenzymes, …

组织非特异性碱性磷酸酶 (TNAP) 在骨骼组织的钙化部位表达。它通过降解无机焦磷酸盐 (PPi) 和增加无机磷酸盐 (Pi) 的浓度来促进羟基磷灰石晶体的形成。然而，Alpl-/-小鼠衍生的成骨细胞 …

Gene ID: 249, updated on 8-Feb-2025. This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, …

2024年3月14日 · We identify the Tissue-Nonspecific Alkaline Phosphatase isozyme (TNAP or ALPL, OMIM 171760), a GPI-anchored protein encoded by the ALPL gene, as the vascular …

Patients were grouped by ALPL variant state (biallelic or monoallelic). Available data from both studies included ALPL pathogenic variant state, Baseline characteristics, HPP-specific medical …

肝/肾/骨型碱性磷酸酯酶（alkaline phosphatase, liver/bone/kidney，ALPL），又称作HOPS、TNAP、APTNAP、TNSALP、AP-TNAP，在骨盐的沉积和矿化中发挥着重要的作用 [7 - 8]。 …