Adeno-associated virus (AAV) vector is the preferred choice for gene therapies of neurological diseases like amyotrophic lateral sclerosis (ALS). Having been committed to gene therapy for decades of years, Creative Biolabs has accumulated experience in offering extensively one-stop AAV vector design and optimization services for the gene ...

2021年6月7日 · Non-viral vectors, such as lipid- and polymer-based nanoparticles, cationic polymers, and exosomes, can effectively transfer genes into primary neurons. The resulting gene expression can be long-term, stable, and without immunological complications, which is essential for the effective management of neurological disorders.

In this review, we provide an in-depth exploration of the state of ALS-directed gene therapy, including antisense oligonucleotides, RNA interference, CRISPR, adeno-associated virus (AAV)-mediated trophic support, and antibody-based methods.

Download free ALS vector logo and icons in PNG, SVG, AI, EPS, CDR formats.

Download free Alternative Learning System (ALS) vector logo and icons in PNG, SVG, AI, EPS, CDR formats.

2006年11月1日 · Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic l -amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat …

The ALS logo in vector format (svg) and transparent PNG. Available for download.

Als logo PNG vector svg with small size (8.06 KB) for free download. You can also download this logo as EPS, AI, PNG, CDR, and PDF formats.

2023年12月13日 · Download Alternative Learning System (ALS) Logo Vector in PNG, SVG, Ai, and EPS formats or you can get all the Logo files in a single zip.

2019年9月6日 · Viral vectors can be used to deliver therapeutic sequences to stably transduce motor neurons in the CNS. Vectors derived from adeno-associated virus (AAV), can efficiently target genes and have been tested in several pre-clinical settings with promising outcomes.