Ambutyrate works by providing an alternative pathway for the body to eliminate ammonia. It helps convert ammonia into a less harmful substance that can be excreted in urine. Ambutyrate is usually taken orally, as prescribed by your doctor. The dosage will depend on your specific condition and response to treatment.

2023年7月21日 · Sodium phenylbutyrate is used in adults and children to treat urea cycle disorders. Sodium phenylbutyrate can be used with other medicines and may also include changes in diet. Sodium phenylbutyrate may also be used for purposes not listed in this medication guide.

Sodium Phenylbutyrate (Ambutyrate) FORM Ampoule containing 2g in 10ml (STOCKED IN RHC NICU) INDICATION Acute hyperammonaemia due to urea cycle disorders DOSE RANGE NB. Treatment should not be initiated without consultation with a metabolic specialist. AGE DOSE FREQUENCY ROUTE 0 – 6 months 250mg/kg Loading dose IV Followed by 10mg/kg/hour

Sodium phenylbutyrate is an ammonia scavenger. The CAS number for sodium phenylbutyrate is 1716-12-7. It is a white or yellowish-white powder and freely soluble in water and in methanol, practically insoluble in methylene chloride. Its pKa is 4.76 and log P is 2.42. Pheburane® granules are sugar-coated spheres containing sodium phenylbutyrate.

Ambrolite Syrup is used for treating various respiratory tract disorders associated with excessive mucus. It works by thinning and loosens mucus in the nose, windpipe, and lungs and make it easier to cough out. Ambrolite Syrup should be taken with food. For better results, it is suggested to take it at the same time every day.

View sodium phenylbutyrate information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, important safety information and directions for administration.

Ambutyrate : Class : Ammonium Detoxicant : Mechanism of Action : Sodium Phenylbutyrate is a prodrug, it is converted to - phenylacetglutamine in the body and serves as a urea substitute. Indications : Adjunctive therapy for maintenance management of urea cycle

2016年10月10日 · Phenylbutyrate and sodium benzoate are orphan drugs approved for the treatment of hyperammonemia in patients with urea cycle disorders, a series of at least 8 rare genetic enzyme deficiencies. The urea cycle is the major pathway of elimination of excess nitrogen including ammonia, and absence of one …

Draw up the required doses of arginine, sodium phenylbutyrate and sodium benzoate and make up to 50mL in the syringe with 5% glucose. The LOADING DOSE gives the approximate equivalent of 20mL/kg of a Normal Saline bolus. The accompanying glucose and fluid quantities of the LOADING DOSE means there is no need to give maintenance fluids.

2024年8月17日 · Ambrolite Syrup is used to treat respiratory conditions that involve excessive mucus production, such as chronic obstructive pulmonary disease (COPD), bronchitis, and asthma. It contains ambroxol, which is a mucolytic agent that helps thin and loosen mucus, making it easier to cough up.