AMD1 Gene - GeneCards | DCAM Protein | DCAM Antibody
Mar 28, 2025 · AMD1 (Adenosylmethionine Decarboxylase 1) is a Protein Coding gene. Diseases associated with AMD1 include Developmental And Epileptic Encephalopathy 87 and Sleeping Sickness. Among its related pathways are Autodegradation of …
腺苷甲硫氨酸脱羧酶 1（AMD1）基因 | MCE - MCE-生物活性 ...
该基因编码多胺生物合成中的一种重要中间酶。 多胺精胺、亚精胺和腐胺是细胞增殖和肿瘤促进所必需的低分子量脂肪胺。 已经鉴定出多个选择性剪接的转录本变体。 该基因的假基因存在于染色体 5、6、10、X 和 Y 上。 [RefSeq 提供，2013 年 12 月] This gene encodes an important intermediate Enzyme in polyamine biosynthesis.
AMD1 adenosylmethionine decarboxylase 1 [ (human)]
Feb 8, 2025 · AMD1 promotes breast cancer aggressiveness via a spermidine-eIF5A hypusination-TCF4 axis. AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth. Polyamine synthesis enzyme AMD1 is closely associated with tumorigenesis and prognosis of human gastric cancers.
AMD1 is required for the maintenance of leukemic stem cells …
Nov 17, 2020 · Here, we found that leukemic stem cells (LSCs) were highly differentiated, and leukemia progression was severely impaired in the absence of AMD1 in vivo. AMD1 was highly upregulated as chronic...
AMD1 mRNA employs ribosome stalling as a mechanism for
Jan 3, 2018 · Here we report a new mechanism that limits the number of complete protein molecules that can be synthesized from a single mRNA molecule of the human AMD1 gene encoding adenosylmethionine...
mTORC1-dependent AMD1 regulation sustains polyamine …
Jun 28, 2017 · AMD1 is upregulated in human prostate cancer with activated mTORC1. Conversely, samples from a clinical trial with the mTORC1 inhibitor everolimus 5 exhibit a predominant decrease in AMD1...
Polyamine synthesis enzyme AMD1 is closely associated with ...
Apr 22, 2020 · Adenosylmethionine decarboxylase 1 (AMD1) is a key enzyme involved in biosynthesis of polyamines including spermidine and spermine. The potential function of AMD1 in human gastric cancers is unknown. We analyzed AMD1 expression level in 319 human gastric cancer samples together with the adjacent nor …
Mus musculus S-adenosylmethionine decarboxylase 1 (Amd1), …
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation. Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W. Clin Transl Med. 2021 Mar; 11(3):e352. AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.
AMD1 adenosylmethionine decarboxylase 1 [ Homo sapiens …
Title: AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth. Polyamine synthesis enzyme AMD1 is closely associated with tumorigenesis and prognosis of human gastric cancers.
Entry - *180980 - S-ADENOSYLMETHIONINE DECARBOXYLASE; AMD1 …
May 25, 2018 · Yordanova et al. (2018) reported a novel mechanism that limits the number of complete protein molecules that can be synthesized from a single mRNA molecule of the human AMD1 gene, encoding adenosylmethionine decarboxylase-1 (AdoMetDC).