Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues.

A rare acute myeloid leukemia that occurs predominantly in childhood and particularly in children with Down syndrome (DS-AMKL). Nonspecific symptoms may be irritability, weakness, and dizziness while specific symptoms include pallor, fever, mucocutaneous bleeding, hepatosplenomegaly, neurological manifestations and rarely lymphadenopathy.

2021年3月31日 · Acute megakaryoblastic leukemia (AMKL), also called acute megakaryocytic leukemia, is a very rare type of blood cancer that most often affects children. About 1 percent of all pediatric leukemias are AMKL. However, adults can also develop this disease.

Acute megakaryoblastic leukemia (AMKL) is a rare malignancy affecting megakaryocytes, platelet-producing cells that reside in the bone marrow. Children with Down syndrome (DS) are particularly prone to developing the disease and have a different age ...

Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) in which cells morphologically resemble abnormal megakaryoblasts. While rare in adults, AMKL accounts for 4-15% of newly diagnosed childhood AML cases.

2023年11月2日 · Background: Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia (AML), commonly observed in children with Down Syndrome (DS) but also seen in adults.

Acute megakaryoblastic leukaemia (AMKL) is a fast-growing blood cancer. It is a rare type of acute myeloid leukaemia (AML). Find out what AMKL is, who might get AMKL and the signs and symptoms of AMKL. We also provide information on how AMKL is diagnosed and treated.

Acute megakaryoblastic leukemia (AML-M7) is defined as an AML in which megakaryoblasts account for ≥50 of the total blast cells [1]. Similar to the other types of AML, total blasts comprise ≥20% of the bone marrow nucleated cells or peripheral blood differential counts. The etiology and pathogenesis of AMKL are not known.

Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia (AML) that occurs predominantly in childhood and particularly in children with Down syndrome (DS-AMKL).

Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues.