2023年8月16日 · What is amphotericin B? Amphotericin B is an antifungal medication that fights infections caused by fungus. Amphotericin B is used to treat serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.

Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. [3] The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. [4] For certain infections it is given with flucytosine. [5] It is typically given intravenously. [4]

2024年2月28日 · Amphotericin B deoxycholate, an esteemed member of the polyene class of antifungals, has been a cornerstone in therapy against invasive fungal infections for over 5 decades. This drug has witnessed significant advancements by introducing novel lipid formulations that exhibit a reduced nephrotoxic profile compared to the traditional formulation.

Amphotericin B is a polyene antifungal agent with activity in vitro against a wide variety of fungal pathogens [1]. Amphotericin B exerts its antifungal effect by disruption of fungal cell wall synthesis because of its ability to bind to sterols, primarily ergosterol, which leads to the formation of pores that allow leakage of cellular components.

Amphotericin B (AMB) is still considered one of the most important antifungals of the last 60 years. We present an overview of the pharmacological properties of the different formulations for systemic use of AMB available for the treatment of invasive fungal infections.

2022年1月3日 · Amphotericin B for Injection USP is specifically intended to treat potentially life-threatening fungal infections: aspergillosis, cryptococcosis (torulosis), North American blastomycosis, systemic candidiasis, coccidioido-mycosis, histoplasmosis, zygomycosis including mucormycosis due to susceptible species of the genera Absidia, Mucor and ...

2019年4月5日 · The first antifungal, amphotericin B deoxycholate, was introduced in 1958. It offers potent, broad-spectrum antifungal activity but is associated with significant renal toxicity and infusion reactions.

Amphotericin B injection is used to treat serious and potentially life-threatening fungal infections. Amphotericin B injection is in a class of medications called antifungals. It works by slowing the growth of fungi that cause infection.

Amphotericin B liposomal is an antifungal medicine that is used to treat serious, life-threatening fungal infections including leishmaniasis, or a certain form of meningitis in people infected with HIV (human immunodeficiency virus).

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