In the genesis of amyloid deposits, previously soluble precursor peptides undergo conformational changes that lead to the adoption of a predominantly antiparallel beta-pleated sheet …

2023年7月24日 · Amyloidosis is the general term used to refer to the extracellular tissue deposition of highly ordered fibrils composed of low molecular weight subunits of a variety of …

2023年2月28日 · Amyloidosis is the abnormal deposition of amyloid (insoluble fibrils comprised of beta-pleated sheets of protein) in extracellular tissues. Amyloid appears microscopically as …

More than 30 distinct low molecular weight proteins are recognized to form amyloid fibrils. The four most common causes of systemic amyloid deposition are: Immunoglobulin light chain (AL) …

2024年4月4日 · A variety of amyloid types are associated with musculoskeletal symptoms, including AL, transthyretin (TTR) amyloidosis (ATTR), and dialysis-related amyloidosis. The …

2024年9月11日 · This topic will review the clinical manifestations, diagnosis, and management of gastrointestinal amyloidosis. Genetic factors, pathogenesis, clinical manifestations, diagnosis, …

2022年7月1日 · In the genesis of amyloid deposits, previously soluble precursor peptides undergo conformational changes that lead to the adoption of a predominantly antiparallel beta-pleated …

This topic will review the treatment and prognosis of cardiac amyloidosis. The pathophysiology of amyloid formation and the clinical manifestations and diagnosis of cardiac amyloidosis are …

2021年10月14日 · Amyloidosis refers to the extracellular tissue deposition of fibrils that are composed of low-molecular-weight subunits (5 to 25 kD) derived from a variety of serum …

2021年3月23日 · Amyloidosis refers to the extracellular deposition of fibrils that are composed of low molecular weight subunits (5 to 25 kD) of a variety of serum proteins. These fibrils adopt a …