2024年12月24日 · ANAPC4 (Anaphase Promoting Complex Subunit 4) is a Protein Coding gene. Diseases associated with ANAPC4 include Adams-Oliver Syndrome. Among its related pathways are CDK-mediated phosphorylation and removal of …

Anaphase-promoting complex subunit 4 is an enzyme that in humans is encoded by the ANAPC4 gene. [ 5 ] [ 6 ] A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are ...

ANAPC4 is a prognostic marker in Breast invasive carcinoma, Colon adenocarcinoma, Liver hepatocellular carcinoma

2022年10月17日 · The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes.

2025年2月9日 · Gene ID: 29945, updated on 9-Feb-2025. A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome.

一种称为后期促进复合物 (APC) 或环状体的大型蛋白质复合物通过泛素化其特定底物 (如有丝分裂细胞周期蛋白和后期抑制剂) 来促进中期-后期转变，这些底物随后被 26S 蛋白酶体降解。 生化研究表明，脊椎动物 APC 包含八个亚基。 APC 的组成在从酵母到人类的生物体中高度保守。 该基因产物的确切功能尚不清楚。 已发现该基因的两个转录本变体编码不同的亚型。 [RefSeq 提供，2013 年 11 月]

2008年9月2日 · Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed: 18485873).

[ANAPC4] A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by …

ANAPC4的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为大蛋白质复合物，称为后期促进复合物（APC），或研究他们，通过泛素其特定的基材，例如有丝分裂细胞周期蛋白和后期抑制剂，其随后通过26S蛋白酶体降解促进中期-后期过渡。 生物化学研究已经表明，在脊椎动物的APC包含八个亚基。 在APC的组合物是高度保守的在从酵母到人类的生物体。 该基因产物的确切功能尚不清楚。 已发现该基因编码不同亚型的两个转录变异体。 [由RefSeq …

2024年12月17日 · View mouse Anapc4 Chr5:52991477-53024076 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression