Androsterone - Wikipedia
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. [1] It is a weak androgen with a potency that is approximately 1/7 that of testosterone. [2] Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT).
The Roles of Androgens in Humans: Biology, Metabolic Regulation …
Androgens are an important and diverse group of steroid hormone molecular species. They play varied functional roles, such as the control of metabolic energy fate and partition, the maintenance of skeletal and body protein and integrity and the development of brain capabilities and behavioral setup (including those factors defining maleness).
雄甾酮 - 维基百科，自由的百科全书
雄酮 （英語： androsterone，3α-hydroxy-5α-androstan-17-one），也称为“ 雄甾酮 ”，是具有较低 雄激素 活性的类固醇 荷尔蒙。 雄酮是肝脏中制造的 睾固酮 代谢物， 它的3-β异构体是 表雄酮，5-β异构体是 本胆烷醇酮，3β,5β-异构体是 表本胆烷醇酮 [1]。 ^ metabocard for Androsterone. Human Metabolome Database. [July 19, 2011]. （原始内容 存档 于2017-07-12）.
Androsterone | C19H30O2 | CID 5879 - PubChem
Androsterone is an androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone. It has a role as an androgen, a human metabolite, a mouse metabolite, an anticonvulsant, a pheromone, a human urinary metabolite and a human blood serum ...
Androgen Receptor Structure, Function and Biology: From Bench …
Androgens (testosterone and dihydrotestosterone (DHT)) are the male sex hormones required for development of the male reproductive system and secondary sexual characteristics. 1 Testosterone can be converted to its more biologically active form, DHT, by 5α reductase, and to oestradiol by aromatase.
Molecular Mechanism of Androgen Action - Cell Press
1998年10月1日 · Androgens affect the growth and development of a wide variety of cell types in both males and females and produce their effects by binding to androgen receptors, which modulate the transcription of specific genes.
Androgen Physiology: Receptor and Metabolic Disorders
2021年7月2日 · Androgens are an important class of C19 steroid hormones that control normal male development and reproductive function. The main circulating androgen is testosterone, which is produced in the Leydig cells of the testis and can also act as a pro-hormone after being metabolized to dihydrotestosterone (DHT) or estradiol (E2).
Biosynthesis and Industrial Production of Androsteroids - PMC
Androsteroids are lipophilic and bind to transport proteins that increase their half-life and ensure ubiquitous distribution throughout the organisms [2]. Mammalian steroid hormones are classified based on their biosynthesis in respective organs, and sex hormones are mainly produced by ovaries and testes [3].
Basics of androgen synthesis and action - ScienceDirect
2022年7月1日 · In the female ovarian theca cells, androstenedione (A4) is produced, where most of it is converted to estradiol by aromatase in the ovarian granulosa cells. Only a small amount of A4 is converted peripherally to T and DHT in hair follicles or in sweat glands.
Androgen Physiology, Pharmacology, Use and Misuse
Testosterone together with its potent metabolite, dihydrotestosterone (DHT), are the principal androgens in the circulation of mature male mammals. Testosterone has a characteristic four ring C18 steroid structure and is synthesized mainly by Leydig cells, located in the interstitium of the testis between the seminiferous tubules.