Autoantigenic gangliosides that are currently known are GD3, GM1, GQ3 and GT1. Anti-GD3 antibodies have been found in association with specific forms of Guillain–Barré syndrome. In vivo studies of isolated anti-GM1 and GD3 antibodies indicate the antibodies can interfere with motor neuron function. [2] .

1988年3月31日 · Gangliosides are thought to have a role in neuronal development and regeneration while anti-ganglioside antibodies have been shown to impair these processes. In the present work we examined whether the neuronal degeneration in Alzheimer's disease is associated with the presence of anti-ganglioside antibodies.

Elevated antibody levels to ganglioside-monosialic acid (GM1) are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals.

National Jewish Health Advanced Diagnostic Laboratories now offers testing for anti-GMCSF autoantibodies. These autoantibodies have been found to be associated with autoimmune pulmonary alveolar proteinosis (PAP). Detection of these autoantibodies in patients’ serum provides additional evidence to support the diagnosis of PAP.

Ganglioside GM1 Antibody refers to specific antibodies that target the GM1 ganglioside, a type of glycosphingolipid found on the surface of neurons. These antibodies are associated with the pure motor or axonal variants of Guillain-Barré Syndrome (GBS). You might find these chapters and articles relevant to this topic.

Anti-ganglioside antibodies (anti-glycolipid antibodies) and peripheral neurophaty Monoclonal antibodies to GM1 gangliosides are associated primarily with disorders affecting motor nerves. They were first described in patients with IgM monoclonal gammopathy and lower motor neuron syndrome and multifocal motor neuropathy (MMN).

We aimed to characterize and investigate the safety and efficacy of Plonmarlimab, a novel anti‐granulocyte‐macrophage colony‐stimulating factor (anti‐GM‐CSF) neutralizing antibody, on the treatment of macrophage activation syndrome (MAS), a life‐threatening systemic inflammatory disease, in pre‐clinical models.

Find the GM-CSF antibody that fits your needs. Choose from 1 of 101 GM-CSF antibodies, which have been validated in experiments with 141 publications and 193 images featured in our data...

Anti-ganglioside antibodies (e.g., anti-GMj) are associated with the development of GBS, and we hypothesized that the swine flu vaccine contained contaminating moieties (such as Campylobacterjejuni antigens that

Anti-mouse GM-CSF-InVivo与小鼠粒细胞巨噬细胞集落刺激因子 (GM-CSF)（也称为集落刺激因子 2 (CSF2)）发生反应。 Quality confirmed by NMR & HPLC. See customer reviews, validations & product citations.