Epithelial polarity - Wikipedia
Epithelial cells feature distinct 'apical', 'lateral' and 'basal' plasma membrane domains. Epithelial cells connect to one another via their lateral membranes to form epithelial sheets that line cavities and surfaces throughout the animal body.
Epithelial polarity, Apical, basal and lateral surfaces of ...
2020年9月8日 · Epithelial cells are one example of the polarized cell type, featuring distinct ‘apical’, ‘lateral’ & ‘basal’ plasma membrane domains. Every plasma membrane domain contains a distinct protein composition, giving them distinct properties & allowing directional transport of molecules across the epithelial sheet.
Apical–basal polarity and the control of epithelial form and ...
2022年4月19日 · Apical–basal polarity in many cells is established by conserved polarity factors that define the apical (Crumbs, Stardust/PALS1, aPKC, PAR-6 and CDC42), junctional (PAR-3) and lateral...
New insights into apical-basal polarization in epithelia
2020年2月1日 · To be able to form selectively permeable barriers, epithelial cells polarize along an apical–basal axis and establish molecularly and functionally distinct apical, basal and lateral membrane domains.
Epithelial Polarity: Interactions Between Junctions and ...
To accomplish this, epithelial cells generate molecularly distinct domains along their plasma membranes: an apical domain that is exposed to the outside, a basolateral domain that contacts the interior, and, in between, an adhesion complex that holds the cell sheet together.
Remodeling Epithelial Cell Organization: Transitions Between ...
Major structures of these cells are also organized in the apical–basal axis: The organization of plasma membrane domains (apical and basolateral), junctional complexes (APC, apical junctional complex), the centrosome (basal body), microtubules and primary cilium, and the secretory pathway (Golgi).
Polarized sorting and trafficking in epithelial cells - PMC
2012年4月24日 · Epithelial cells employ an elaborate trafficking system to control the distribution of proteins and lipids to their apical and basolateral surface domains, which is an important determinant of cell polarity.