Aquaporins, also called water channels, are channel proteins from a larger family of major intrinsic proteins that form pores in the membrane of biological cells, mainly facilitating transport of water between cells. [1]

2013年1月21日 · Aquaporins (often called aquaporin water channels) are a family of small, integral membrane proteins that are expressed broadly throughout the animal and plant kingdoms. They have a similar basic structure, with aquaporin monomers consisting of six transmembrane helical segments and two short helical segments that surround cytoplasmic …

2016年12月30日 · Aquaporins are a very lucky family of membrane proteins, which are notoriously resistant against structure determination. We have now high resolution structures of several AQPs: GlpF, AQP1, AQP0, and AqpZ.

Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as various small solutes in a bidirectional manner are widely distributed ...

The aquaporins (AQPs) are a family of small membrane-spanning proteins (monomer size approximately 30 kDa) that are expressed at plasma membranes in many cells types involved in fluid transport. This review is focused on the molecular structure and …

The atomic structure of AQP1 protein provides marked insight into several human disease states. Ten other aquaporin genes are also expressed in humans, and their structures are expected to be very similar.

2004年9月1日 · Eleven mammalian aquaporins have been identified so far and they have cellular and subcellular distributions in different organs that indicate probable functional roles. Studies in animals and...

Aquaporin provides a proteinaceous pathway for water. They are of a similar basic structure, consisting of a narrow aqueous pore that is connected to the cytoplasmic and extracellular vestibules surrounded by aquaporin monomers containing six transmembrane and two short helical segments.

The ubiquitous members of the aquaporin (AQP) family form transmembrane pores that are either exclusive for water (aquaporins) or are also permeable for other small neutral solutes such as glycerol (aquaglyceroporins).

1999年10月1日 · A combination of sequence analysis, three-dimensional structure determination, and physiology of the AQP family proteins provides a glimpse into the workings of water channels. Every living cell must deal with the osmotic and hydrostatic pressure changes in its environment.