critically appraise the ocular safety and efficacy of aqueous chlorhexidine. Main Outcome Measures: Incidence of endophthalmitis after intravitreal injections. Results: A total of 40535 intravitreal injections were performed by 7 retinal specialists across 3 centers.

We compared alcoholic chlorhexidine with aqueous chlorhexidine for skin antisepsis to prevent surgical site infection after minor skin excisions in general practice. We conducted this prospective, multicentre, randomized controlled trial in 4 private general practices in North Queensland, Australia, from October 2015 to August 2016.

2016年6月6日 · In the present series, we found that aqueous chlorhexidine 0.05% or 0.1% used for the prophylaxis of endophthalmitis after intravitreal injection was well tolerated and associated with an endophthalmitis rate lower than many previous series in which PI has been used.

1% aqueous chlorhexidine gluconate (CHG) is not non-inferior to 2% aqueous CHG for skin antisepsis in neonates. Aqueous chlorhexidine does not cause significant adverse skin reactions in neonates, especially in neonates born at gestational age ≥28 weeks.

Purpose: To determine the incidence of endophthalmitis in a large clinical series using aqueous chlorhexidine for antisepsis before intravitreal injection and to review the ophthalmic literature regarding chlorhexidine efficacy and safety.

2024年9月20日 · Aqueous chlorhexidine has comparable antiseptic efficacy to alcohol-based chlorhexidine. Systemic absorption of chlorhexidine is of concern, especially in preterm neonates, due to skin...

2022年2月19日 · To compare 2% aqueous chlorhexidine gluconate (AQC) vs. 2% chlorhexidine gluconate in 70% isopropyl alcohol (ALC) for pre-venipuncture skin antisepsis in very-low-birth-weight neonates (VLBW,...

Aqueous chlorhexidine (AqCHX) has been described as a possibly better tolerated antimicrobial for ophthalmic procedures. We compared patient pain scores, ocular surface characteristics, and antimicrobial efficacy between PI 5% and AqCHX 0.1% during IVIs.

2016年3月7日 · We have found chlorhexidine gluconate (0.1%) is safe and efficacious antisepsis prophylaxis for IVI, particularly for those patients with betadine sensitivity in whom the significance of postprocedure pain should not be underestimated. We have also successfully used chlorhexidine gluconate 0.1% for cataract surgery antisepsis.

2024年12月13日 · Aqueous chlorhexidine (AC) has become a popular alternative to PI in many retina practices, with several large studies showing equivalent post-injection endophthalmitis rates. 16,17 In my (Dr. Liu’s) clinical experience, patient complaints in the hours post-injection have decreased significantly with the switch from PI to AC.