2021年7月15日 · We treated V-K562 cells or B-K562 cells with atorvastatin, an inhibitor of HMG-CoA reductase (the rate-limiting enzyme in cholesterol biosynthesis) and determined the effect …

2012年9月27日 · WT1 occupied the AREG, Ets-1, VDR, and JunB promoter regions in both vector control K562 cells and BASP1-expressing K562 cells. In addition, K562 cells expressing …

Immunoblotting of whole-cell extracts with anti-prohibitin antibodies confirmed the depletion of prohibitin by both siRNAs . 48 hours after transfection, cDNA was produced and the …

genesamphiregulin(AREG),Ets-1,VitaminDreceptor(VDR),and JunB, along with Bax as a control non-WT1 target gene (Fig-ure 3A). As we reported in a recent study (Goodfellow et al., 2011), …

Immunoblotting of whole-cell extracts with anti-prohibitin. antibodies confirmed the depletion of prohibitin by both siRNAs (Figure 2). Forty-eight hours after transfection, cDNA was produced …

Primers used for ChIP analysis AREG, gene encoding amphiregulin. [...] The Wilms' tumour suppressor WT1 (Wilms' tumour 1) is a transcriptional regulator that plays a central role in...

2012年9月27日 · In this study, we demonstrate that the N-terminal myristoylation of BASP1 and the capacity of BASP1 to interact with PIP2 are critical for its transcriptional corepressor …

2010年10月15日 · Induction of Ets1 during embryonic development results in a dramatic alteration in epidermal structure and function by suppressing the expression of multiple stratum corneum …

2014年10月10日 · Immunoblotting of whole-cell extracts with anti-prohibitin antibodies confirmed the depletion of prohibitin by both siRNAs (Figure 2). 48 hours after transfection, cDNA was …

They bind the DNA via their winged-helix-turn-helix DNA binding motif known as the Ets domain that specifically recognizes DNA sequences that contain a GGAA/T core element. However, …