FGF7 signals are relayed to autocrine EGF family growth factors to ...
2013年11月14日 · In the present study, using epithelium-alone cultures, we showed that exogenous FGF7 was relayed by autocrine EGF family growth factors that directly induced …
Identifying the effectiveness of 3D culture systems to recapitulate ...
2023年9月30日 · To empirically identify optimal culture conditions, we performed growth factor and cytokine analysis from isolated normal and cancer-associated (CAF) stromal fibroblasts. …
Alveolar cell fate selection and lifelong maintenance of AT2 cells …
2022年11月21日 · FGF signaling directly and cell autonomously specifies AT2 fate; progenitors lacking Fgfr2 in vitro and in vivo exclusively acquire AT1 fate. Fgfr2 loss in AT2 cells …
Sustained activation of the HER1–ERK1/2–RSK signaling pathway …
2011年8月1日 · FGF7 with AREG generated ducts that had larger lumens than FGF7 alone but still had a disorganized cellular structure with large gaps in the myoepithelial layer. These data …
The Gene Expression Program of Prostate Fibroblast Senescence …
2006年1月19日 · Other senescence-induced mitogenic factors identified in this study include FGF7/KGF, IGFBPs, and AREG. AREG is a heparin-binding member of the epidermal growth …
Amphiregulin-producing regulatory T cells guide alveolar …
In the absence of Treg–derived Areg, Col14+ cells exhibit aberrant transcriptional programming, reduced expression of important alveolar growth factors, Fgf7 and Fgf10, and a dramatic …
了不起的成纤维细胞生长因子(FGF)家族 - 知乎 - 知乎专栏
fgf7亚科：fgf7家族由fgf3，7，10，22组成。fgf3，7，10，22优先激活fgf受体2和fgf3和fgf10的b期剪接变异体，也激活fgf受体1的b期剪接变异体。 FGF3，7，10，22优先激活FGF受体2 …
The ADAM17–amphiregulin–EGFR Axis in Mammary Development …
The epidermal growth factor receptor (EGFR/ErbB1) is a transmembrane tyrosine kinase that elicits its intracellular and downstream signaling effects upon binding one of seven possible …
EGF regulates myoepithelial lineage determination. ( A ) …
In the presence of AREG plus FGF2/FGF7, the tight junction marker ZO-1 correctly localizes at the apical boundaries of luminal epithelial cells and the majority of the cells in the luminal...
茁彩ELISA 系列ㅣ双调蛋白 (Amphiregulin, AREG) - 知乎
2023年6月6日 · 双调蛋白 (Amphiregulin, AREG) 是一种表皮生长因子 (EGF) 样分子，属于EGF家族。 它是一种自分泌生长因子，也是星形胶质细胞、雪旺细胞和成纤维细胞的有丝分裂原。