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企业资讯丨普沐生物：揭示肺纤维化全新靶点作用机制，靶点新药P…
2024年8月3日 · 该研究系统性地阐述了公司开发用于治疗特发性肺纤维化 (Idiopathic Pulmonary Fibrosis，IPF)的全球首创（first-in-class）新药PMG1015所针对的靶 …
Amphiregulin couples IL1RL1 - Science
2023年8月23日 · Whole tumor single-cell RNA sequencing (scRNA-seq) analysis and blockade experiments revealed that the amphiregulin (AREG)–epidermal growth factor receptor (EGFR) …
Sustained amphiregulin expression in intermediate alveolar stem …
2024年9月5日 · We showed that amphiregulin (AREG) expression is significantly elevated in intermediate alveolar stem cells of mouse fibrotic lungs and IPF patients. High levels of serum …
茁彩ELISA 系列ㅣ双调蛋白 (Amphiregulin, AREG) - 知乎
2023年6月6日 · 双调蛋白 (Amphiregulin, AREG) 是一种表皮生长因子 (EGF) 样分子，属于EGF家族。 它是一种自分泌生长因子，也是星形胶质细胞、雪旺细胞和成纤维细胞的有丝分裂原。
Amphiregulin orchestrates the paracrine immune-suppressive …
The results highlight the immunosuppressive efficacy of PGE 2 -dependent AREG release, dampening PBMCs’ activation, and NFAT pathway in Jurkat reporter cells via TGF-β signaling. …
Amphiregulin - PubMed
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored …
Amphiregulin in cellular physiology, health, and disease ... - PubMed
Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. AREG is …
双调蛋白（AREG）或可成为西妥昔单抗治疗结直肠癌的疗效预测 …
2022年1月14日 · 近期，发表于 Scientific Reports 上的一项研究结果提示，血浆双调蛋白（AREG）是预测西妥昔单抗治疗临床结果的潜在生物标志物。 研究目的. AREG是一 …
Emerging Functions of Amphiregulin in Orchestrating Immunity ...
2015年2月17日 · Emerging data suggest that in addition to characteristic type 2-associated cytokines, the epidermal growth factor (EGF)-like molecule Amphiregulin (AREG) might be a …