2022年1月10日 · The expression of Arg1 in G-MDSCs from different tissues was detected, and the results showed that Arg1 expression was gradually upregulated in bone marrow, …

2020年5月15日 · In this study, we first analyzed by flow cytometry the phenotype and the ARG1 expression level in MDSCs from peripheral blood and cancerous tissue of gastric …

Results: We show that: i) Arg1+ macrophages are more abundant in tumors compared to other organs; ii) there exist two morphologically distinct subsets of Arg1 TAM defined by previously …

2023年4月15日 · On one hand, the responsive released L-norvaline from the hydrogel skeleton powerfully inhibited enzyme ARG1 activity to block the depletion of L-arginine by ARG1 …

2024年7月1日 · Both show elevated arginase type 1 (Arg1) expression, which induces nitric oxide synthase (iNOS) or indoleamine 2,3-dioxygenase 1 (IDO) expression. iNOS and IDO can …

2018年11月12日 · In growing tumors, TAM are often referred to as M2-like macrophages, which are cells that display immunosuppressive and tumorigenic functions and express the enzyme …

2019年9月17日 · Human monoclonal Abs against Arg1-Alexa Fluor 488 (Cat no. 53369782, invitrogen) and iNOS (Cat no. MA517139, Invitrogen) were used for FCM analysis for Arg1 …

2022年11月16日 · Increased arginase activity has been associated with potent suppression of T-cell immune responses in different types of cancer. Here, we investigated the role of arginase …

2020年5月15日 · In this study, we first analyzed by flow cytometry the phenotype and the ARG1 expression level in MDSCs from peripheral blood and cancerous tissue of gastric …

2022年1月12日 · Moreover, the levels of IL4 and IL10 were detected by FCM (Figure S1d). FCM showed that the percentage of CD206 + macrophages (M2) was enhanced obviously after …