2024年12月24日 · ARHGEF2 (Rho/Rac Guanine Nucleotide Exchange Factor 2) is a Protein Coding gene. Diseases associated with ARHGEF2 include Neurodevelopmental Disorder With …

2022年11月5日 · ARHGEF2 is transcriptionally repressed by AR, and the AR-targeted therapy relieves this repression leading to ARHGEF2 up-regulation. In addition, experiments …

Rho guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ARHGEF2 gene. [5] [6] [7]

Our results highlight the crucial function of ARHGEF2 in human brain development and identify a mutation in ARHGEF2 as novel cause of a neurodevelopmental disorder. Overexpression of …

Rho/Rac 鸟嘌呤核苷酸交换因子 2： Rho GTP 酶在许多细胞过程中起着重要作用，这些过程由通过 G 蛋白偶联受体起作用的细胞外刺激物启动。编码的蛋白质可能与 G 蛋白形成复合物并刺 …

2022年7月27日 · Elevated ARHGEF2 accelerates HCC angiogenesis via the EDN1 pathway, enhances HCC cell proliferation and tumor growth both in vitro and in vivo, and contributes to …

To test whether the genetic removal of Arhgef2 affects neurite branching and synapse formation during neural differentiation, we examined the morphology of cortical neurites and dendrite …

The PAR-1-MARK pathway controls cell polarity through the phosphorylation of microtubule-associated proteins. The Rho-Rac guanine nucleotide exchange factor 2 (ARHGEF2), which …

2024年3月5日 · Title: High ARHGEF2 (GEF-H1) Expression is Associated with Poor Prognosis Via Cell Cycle Regulation in Patients with Pancreatic Cancer. The RhoA regulators Myo9b and …

ARHGEF2 (synonym GEF-H1, murine Lfc), a member of the Rho guanine nucleotide exchange factor family, is crucial for controlling the spatiotemporal activation of Rho GTPases (Ren et …