2025年1月15日 · In this Review, we summarize the emerging chemistry of aromatic side-chain crosslinking in RiPP biosynthetic pathways. We discuss in detail the rSAM, P450, burpitide …

Here, we re-evaluate the geometry and energetics of these interactions using quantum mechanical (QM) calculations, focusing on pairwise interactions involving the aromatic amino …

2017年6月26日 · Tyr is an essential aromatic amino acid required for protein synthesis in all organisms but synthesized de novo only in plants and microorganisms 7,8.

2025年3月10日 · In this work, we systematically investigate this relationship by synthesizing CDs using two aromatic amino acids with distinct reactive sites, phenylalanine (Phe) and tyrosine …

The aromatic amino acids phenylalanine, tyrosine and tryptophan in plants are not only essential components of protein synthesis, but also serve as precursors for a wide range of secondary …

2007年6月1日 · The side chains of the aromatic amino acids [phenylalanine (Phe), tyrosine (Tyr), and tryptophan (Trp)] provide a surface of negative electrostatic potential than can bind to a …

In the present work, we compare the results for Trp/Tyr with the consequences of Phe substitutions at positions 4 and 5 in GWALP23. Additionally, we examine the consequences of …

2020年5月8日 · Previous work from our group, extended original studies of pairs of aromatic interactions, showing that inside proteins (intraprotein), aromatic rings (derived from Phe, Tyr, …

2015年9月24日 · One of the significant non-covalent forces between the protein side chains is aromatic–aromatic interactions. Aromatic interactions have been widely exploited and …

The aromatic amino acids L-tryptophan (Trp), L-tyrosine (Tyr), and L-phenylalanine (Phe) serve as direct or indirect precursors of neurotransmitters and hormones such as serotonin (Trp), or …