Cucurbitacins are multiplex category of diverse compounds found in the plants of family Cucurbitaceae. Medicinal and toxic properties of these compounds have stimulated a continuing interest in them. [1] . Many genus of Cucurbits viz. Trichosanthes, Cucurbita, Cucumis and Citrullus are affluent in cucurbitacins.

Cucurbitacins are a class of biochemical compounds that some plants – notably members of the pumpkin and gourd family, Cucurbitaceae – produce and which function as a defense against herbivores.

2016年11月28日 · Differentiation of secondary metabolite profiles in closely related plant species provides clues for unravelling biosynthetic pathways and regulatory circuits, an area that is still...

Cucurbitacin B and cucurbitacin E have been identified as the most investigated when it comes to the immune response, playing roles in both innate and adaptive immunity. The most cited mechanisms were inhibition of COX-2 and NOS, reduction of oxidative stress, suppression of proinflammatory cytokines and modulation of acquired immunity proteins.

Cucurbitacins are highly oxidized tetracyclic triterpenoids that are widely present in traditional Chinese medicines (Cucurbitaceae family), possess strong anticancer activity, and are divided into 12 classes from A to T with over 200 derivatives.

2023年1月1日 · Cucurbitacin B is the main active component isolated from Cucumis mello L. Research shows that cucurbitacin B exerts powerful anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective and anticancer pharmacological activities through regulating multiple signaling transduction pathways, such as JAK/STAT3, Nrf2/ARE...

2022年12月31日 · Cucurbitacin B isolated from Trichosanthes cucumerina (snake gourd) is the greatest source of cucurbitacins, which ensued the attention of scientists because of its several anticancer mechanisms [14, 15].

Cucurbitacins are a class of highly oxygenated compounds, with a tetracyclic triterpenic structure derived from the cucurbitane skeleton [19- (10→9β)-abeo-l0α-lanost-5-ene] also known as 9β-methyl-19-nor lanosta-5-ene (Figure 2).

Cucurbitacin refers to a group of triterpenoids found primarily in the Cucurbitaceae plant family, known for their bitter taste. They have various properties, including being toxic to insects and mammals, and have shown potential as anticancer agents. You might find these chapters and articles relevant to this topic. Kunisuke Izawa, ...

2019年11月26日 · Tujuan penelitian adalah untuk menganalisis perbedaan kandungan protein, asam amino, dan daya terima dari PMT-P berbasis labu kuning dengan tiga macam formulasi. Metode: Tiga macam formulasi—20% biji labu (A1); 25% biji labu (A2); 30% biji labu (A3) —diuji dalam eksperimen rancangan acak lengkap dengan tiga ulangan, kecuali untuk uji ...