2024年12月24日 · ATF6 (Activating Transcription Factor 6) is a Protein Coding gene. Diseases associated with ATF6 include Achromatopsia 7 and Achromatopsia. Among its related …

Activating transcription factor 6, also known as ATF6, is a protein that, in humans, is encoded by the ATF6 gene [5][6][7] and is involved in the unfolded protein response. ATF6 is an …

2024年3月15日 · Activating transcription factor 6 (ATF6), an important signaling molecule in unfolded protein response (UPR), plays a role in the pathogenesis of several diseases, …

2024年12月10日 · Activating transcription factor 6 regulated cell growth, migration and inhibiteds cell apoptosis and autophagy via MAPK pathway in cervical cancer. Liu F, et al. J Reprod …

2018年1月11日 · 该研究首次绘制了多种人干细胞和体细胞受内质网应激蛋白ATF6调控的基因表达图谱，揭示了ATF6维持多种细胞器稳态的新型机制，为衰老和老年性疾病的研究和干预提供 …

ATF6 is a type II transmembrane protein, which under basal conditions associates with BiP. The accumulation of unfolded proteins initiates the dissociation of ATF6 from BiP and the reduction …

激活转录因子 6 (ATF6) 是内质网 (ER) 中的三种传感器蛋白之一，是 ER 应激诱导的细胞凋亡途径中的重要调节因子。 尽管近期研究在阐明ATF6的调控机制方面取得了一些进展，但内质网应 …

ATF6 (N) is a basic leucine zipper (bZIP)–class transcriptional activator that, once untethered from the membrane, migrates to the nucleus to up-regulate ER protein–folding chaperones …

ATF6, a member of the leucine zipper protein family, can constitutively induce the promoter of glucose-regulated protein (grp) genes through activation of the endoplasmic reticulum (ER) …

它们包括：肌醇需求酶1α（IRE1α）、蛋白激酶R样内质网激酶（PERK）和激活转录因子6（AFT6）。 CHOP，Caspase-12和JNK是三个与ER相关的信号通路。 研究表明，内质网应 …