ATGAM can cause potentially life‑threatening anaphylaxis when injected intravenously. Monitor patients for signs and symptoms of anaphylaxis during infusion and for at least 24 hours after infusion. IV=intravenous. Reference: ATGAM [prescribing …

2023年9月20日 · Atgam is a polyclonal antibody, or an immune globulin, given as an intravenous (IV, into a vein) infusion. Atgam is used to fight a type of white blood cell called a T-lymphocyte (also called a thymocyte or T-cell).

ATGAM sterile solution contains lymphocyte immune globulin, anti-thymocyte globulin (equine). It is the purified, concentrated, and sterile gamma globulin, primarily monomeric IgG, from hyperimmune serum of horses immunized with human thymus lymphocytes. ATGAM is a transparent to slightly opalescent aqueous protein solution.

For intravenous use only. Administer ATGAM intravenously and use with concomitant immunosuppressants. The recommended dose is 10 to 15 mg/kg daily intravenously for 14 days. Additional alternate-day therapy up to a total of 21 doses may be given. The recommended dose is 10 to 20 mg/kg daily intravenously for 8 to 14 days.

Renal allograft rejection Aplastic anemia (moderate to severe) in patients unsuitable for bone marrow transplantation. Limitations of Use: The usefulness of ATGAM has not been demonstrated in...

Administer ATGAM intravenously and use with concomitant immunosuppressants. The recommended dose is 10 to 5 mg/kg daily intravenously for 14 days. Additional alternate-day therapy up to a total of 21 doses may be given.

2024年6月18日 · ATGAM Sterile Solution contains lymphocyte immune globulin, anti-thymocyte globulin [equine]. It is the purified, concentrated, and sterile gamma globulin, primarily monomeric IgG, from hyperimmune serum of horses immunized with human thymus lymphocytes. ATGAM is a transparent to slightly opalescent aqueous protein solution.

ATGAM is intended for intravenous use only. ATGAM is used with concomitant immunosuppressants. During repeat courses of ATGAM, observe patients for signs of allergic reactions [see Warnings and Precautions (5.1)]. Renal transplant rejection: The recommended dose is 10 to 15 mg/kg daily intravenously for 14 days.

2023年12月12日 · Atgam has induced instances of partial or complete haematologic recovery and improved survival in patients with aplastic anaemia of known or suspected immunologic aetiology in patients who are unsuitable for bone marrow transplant.

2023年9月5日 · ATGAM sterile solution contains lymphocyte immune globulin, anti-thymocyte globulin [equine]. It is the purified, concentrated, and sterile gamma globulin, primarily monomeric IgG, from...