Fever, chills, and erythematous or urticarial rash were seen in all ATGAM treated patients. Platelet counts decreased during ATGAM infusion and daily platelet transfusions were necessary. Serum sickness occurred in all patients within 6 to 18 days of ATGAM initiation and was well-controlled with standard therapy.

The most commonly reported adverse reactions (occurring in greater than 10% of patients) are pyrexia, chills, rash, thrombocytopenia, leukopenia, and arthralgia. Table 1. Adverse Reactions Occurring in ≥1% of Patients Who Received ATGAM. Table 2. Adverse Reactions Occurring in <1% of Patients Who Received ATGAM.

Serious infusion-associated reactions have been reported with the use of ATGAM. Clinical signs associated with infusion-associated reactions include generalized rash, tachycardia, dyspnea, and hypotension. Monitor patients for signs and symptoms of infusion-associated reactions and manage according to relevant clinical guidelines.

2024年5月10日 · Side effects include: Renal allotransplantation: Fever, chills, leukopenia, thrombocytopenia, dermatologic reactions (rash, pruritus, urticaria, wheal and flare). Aplastic anemia: Fever, chills, skin reactions, arthralgia, headache, myalgia, nausea, chest pain, phlebitis, serum sickness. Managing side effects (general information)

Incidence greater than 5%: fever (33%), chills (14%), leukopenia (14%), thrombocytopenia (11%), dermatological reactions such as rash, pruritus, urticaria, wheal and flare (12.5%). Incidence of 1 to 5%: arthralgia, chest and/or back pain, clotted A/V fistula, diarrhea, dyspnea, headache, hypotension, nausea and/or vomiting, night sweats, pain ...

ATGAM is indicated for the treatment of moderate to severe aplastic anemia in patients unsuitable for bone marrow transplantation [see Clinical Studies (14.2)].

2023年12月9日 · Easy-to-read patient leaflet for Atgam. Includes indications, proper use, special instructions, precautions, and possible side effects.

2023年12月12日 · A systemic reaction such as a generalized rash, tachycardia, dyspnoea, hypotension, or anaphylaxis precludes any additional administration of Atgam. It is recommended to administer corticosteroids and antihistamines prior to infusion of …

Fever, chills, and erythematous or urticarial rash were seen in all ATGAM treated patients. Platelet counts decreased during ATGAM infusion and daily platelet transfusions were necessary. Serum sickness occurred in all patients within 6 to 18 days of ATGAM initiation and was well-controlled with standard therapy.

You may have a rash, joint pain, muscle aches, and feel tired. Blood clots (rare); A blood clot in your leg may cause your leg to swell, appear red and warm, and/or cause pain. A blood clot in your lungs may cause shortness of breath, pain when breathing, and/or chest pain.