Objective: Atonic postpartum hemorrhage rates have increased in many industrialized countries in recent years. We examined the blood loss, risk factors, and management of the third stage of labour associated with atonic postpartum hemorrhage.

PPH is generally defined as blood loss greater than or equal to 500 ml within 24 hours after birth, while severe PPH is blood loss greater than or equal to 1000 ml within 24 hours. PPH is the most common cause of maternal death worldwide. Most cases of morbidity and mortality due to PPH occur in the first 24 hours following delivery and

Forty-seven potential risk factors for atonic postpartum hemorrhage were identified in this review, of which 15 were judged definite or likely risk factors. The remaining 32 assessed risk factors showed no association with atonic postpartum hemorrhage or had conflicting or unclear evidence.

We identified novel biomarkers and developed predictive models for atonic PPH in women undergoing “low-risk” vaginal delivery, providing immunological insights for further exploration of the mechanism underlying atonic PPH.

Primary postpartum haemorrhage (PPH) is the most common form of major obstetric haemorrhage. The traditional definition of primary PPH is the loss of 500 ml or more of blood from the genital tract within 24 hours of the birth of a baby after vaginal birth and 1000 ml after cesarean birth. PPH can be minor (500–1000 ml) or

2025年1月30日 · Postpartum hemorrhage (PPH) is the leading cause of maternal mortality worldwide, accounting for approximately 18% , with 60 -70% of cases being atonic PPH (caused by uterine atony) . Early prediction and identification of PPH are the basis for timely and effective rescue, but currently there is a lack of effective prediction models for atonic PPH.

2021年2月1日 · Many risk factors for atonic hemorrhage included in current risk-assessment tools were confirmed, with the greatest risk conferred by prior postpartum hemorrhage of any etiology, placenta previa, placental abruption, uterine rupture, and multiple gestation.

The main cause of PPH is uterine atony, i.e., the failure of the uterus to contract efficiently after placenta delivery, which is known as atonic PPH [17,18,19]. PPH commonly lasts for 24 h, which is called immediate PPH, but there are instances of hemorrhage for up to six weeks after delivery, which is known as delayed PPH [ 20 ].

The traditional WHO definition of primary PPH is the loss of 500 ml or more of blood from the genital tract within 24 hours of the birth of a baby. PPH can be minor (500–1000 ml) or major (more than 1000 ml).

2020年8月1日 · When compared to existing prophylaxis uterotonics, intravenous carbetocin was listed as one of the three most highly ranked uterotonics for PPH prevention and is as effective as oxytocin for PPH prevention, regardless of severity, without an increase in side effects or need for additional uterotonics.