2024年12月24日 · ATP6AP2 (ATPase H+ Transporting Accessory Protein 2) is a Protein Coding gene. Diseases associated with ATP6AP2 include Parkinsonism With Spasticity, X-Linked and Congenital Disorder Of Glycosylation, Type Iir. Among its related pathways are Innate Immune System and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics.

2024年5月29日 · ATP6AP2, an accessory subunit of V-ATPase, plays important roles in multiple cell types/organs and multiple signaling pathways. However, little is known whether and how ATP6AP2 in OBs regulates...

2025年2月9日 · Results suggest that full-length ATP6AP2 contributes to the assembly of the V-ATPase proton pore and that impairment of this function affects ER homeostasis and PCP signaling. Data show that TMEM9 binds to and facilitates assembly of vacuolar-ATPase (v-ATPase), a vacuolar proton pump, resulting in enhanced vesicular acidification and trafficking

2021年8月1日 · The ATP6ap2 (Pro)renin receptor protein associates with H +-ATPases which regulate organellar, cellular, and systemic acid-base homeostasis. In the kidney, ATP6ap2 colocalizes with H + -ATPases in various cell types including the cells of the proximal tubule.

ATP6AP2 Protein, Human (His) is the recombinant human-derived ATP6AP2 protein, expressed by E. coli, with N-6*His labeled tag. The total length of ATP6AP2 Protein, Human (His) is 334 a.a., with molecular weight of ~40 kDa.

ATP6AP2, an accessory subunit of V-ATPase, plays important roles in multiple cell types/organs and multiple signaling pathways. However, little is known whether and how ATP6AP2 in OBs regulates Wnt/β-catenin signaling and bone formation.

该基因编码一种与三磷酸腺苷酶 (ATPases) 相关的蛋白质。 质子转运 ATP 酶在能量守恒、二次主动转运、细胞内区室酸化和细胞 pH 稳态中具有重要作用。 存在三类 ATP 酶 - F、P 和 V。 液泡 (V 型) ATP 酶具有跨膜质子传导部分和膜外催化部分。 已发现编码的蛋白质与 V 型 ATP 酶的跨膜区有关。 [RefSeq 提供，2008 年 7 月] This gene encodes a protein that is associated with adenosine triphosphatases (ATPases).

（原）肾素受体 [（P）RR， Atp6ap2] 最初被发现是肾素原和肾素的膜结合伴侣。A 可溶性 （P）RR 具有额外的旁分泌作用，并参与代谢综合征和肾脏损伤同时，很明显，（P）RR 的大部分作用与肾素无关。

2024年5月29日 · ATP6AP2, an accessory subunit of V-ATPase, plays important roles in multiple cell types/organs and multiple signaling pathways. However, little is known whether and how ATP6AP2 in OBs regulates Wnt/β-catenin signaling and bone formation.

Orthologous to human ATP6AP2 (ATPase H+ transporting accessory protein 2). [provided by Alliance of Genome Resources, Apr 2022] — Master of Bioactive Molecules