Pill with imprint b 973 2 0 is Orange, Oval and has been identified as Amphetamine and Dextroamphetamine 20 mg. It is supplied by Teva Pharmaceuticals USA. Amphetamine/dextroamphetamine is used in the treatment of ADHD; Narcolepsy and belongs to the drug class CNS stimulants. Risk cannot be ruled out during pregnancy.

B-973 is an efficacious type II positive allosteric modulator (PAM) of α 7 nicotinic acetylcholine receptors that, like 4BP-TQS and its active isomer GAT107, can produce direct allosteric activation in addition to potentiation of orthosteric agonist activity, which identifies it as an allosteric activating (ago)-PAM.

Take this medication by mouth with or without food as directed by your doctor, usually 1 to 3 times a day. The first dose is usually taken when you wake up in the morning. If more doses are...

This orange elliptical / oval pill with imprint b 973 2 0 on it has been identified as: Amphetamine/dextroamphetamine 20 mg. This medicine is known as …

2017年3月15日 · Here we describe 3- (3,4-difluorophenyl)-N- (1- (6- (4- (pyridin-2-yl)piperazin-1-yl)pyrazin-2-yl)ethyl)propanamide (B-973), a novel piperazine-containing molecule that acts as a positive allosteric modulator of the α7 receptor. We characterize the action of B-973 on the α7 receptor using electrophysiology and radioligand binding.

B 973B is a positive allosteric modulator of α7 nAChRs (EC 50 ~0.3 μM); active enantiomer. Increases potency of acetylcholine (EC 50 values are 0.007 mM and 0.3 mM in the presence and absence of B 937B, respectively).

2018年10月11日 · We report here the total synthesis of B-973 (five steps), a recently identified α7 nAChR ago-PAM, its enantiomeric resolution, and its electrophysiological characterization in Xenopus oocytes to id...

(-)- (S)-B-973B 为一种有效的 α7 nAChR 正向别构调节剂，可用于缓解疼痛的研究。

B-973: a α7 receptor modulators Drug, Initially developed by Bristol Myers Squibb Co., Now, its global highest R&D status is Preclinical, Mechanism: α7 receptor modulators (Neuronal acetylcholine receptor protein alpha-7 subunit modulators), Therapeutic Areas: Nervous System Diseases, Active Indication: Alzheimer Disease,Schizophrenia, Active ...

B-973是由百时美施贵宝研发的一种小分子药物，是一种nAChRα7调节剂。 目前该药物最高研发阶段为临床前，用于治疗认知障碍。