Neuromedin regulates the following functions: NMB acts by binding to its high affinity cell surface receptor, neuromedin B receptor (NMBR). This receptor is a G protein-coupled receptor with seven transmembrane spanning regions, hence the receptor is also denoted as a 7-transmembrane receptor (7-TMR).

2024年12月25日 · NMB (Neuromedin B) is a Protein Coding gene. Diseases associated with NMB include Gastrinoma and Urethral False Passage. Among its related pathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). Gene Ontology (GO) annotations related to this gene include hormone activity and neuromedin B receptor binding.

Neuromedin B 与 Bombesin (BN) 相比，可刺激大鼠子宫平滑肌收缩。 以 BN 为 100 计算的相对效力为，GRP 为 48%，Neuromedin B 为 4.9%。 Neuromedin B 对大鼠胃条也有收缩活性，但效力 (EC 50) 仅为 BN 的 5% (BN 的 EC 50 比 Neuromedin B 的 EC 50)，约为 GRP 的 10% (GRP 的 EC 50 比 Neuromedin B 的 EC 50) [1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2022年6月7日 · Neuromedin B (NMB) is a member of the neuromedin family of neuropeptides with a high level of region-specific expression in the brain. Several GWAS studies on non-obese and obese...

This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity.

Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal tract. BN and its related peptides have various physiological effects.

2000年10月31日 · Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal tract. BN and its related peptides have various physiological effects.

Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal tract. BN and its related peptides have various physiological effects.

美国 新泽西州立大学 Mark C. Siracusa博士领导的团队最近研究了II型免疫应答如何参与神经调节肽B（NMB）的表达，这种蛋白可防止过度活跃的免疫应答和破坏性炎症。

This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth.