
B16 as a Mouse Model for Human Melanoma - PMC
2021年10月19日 · B16 melanoma is one of the very few pigmented melanoma lines available for use in mice, although recently transgenic models have been developed in which the reliable …
B16 as a mouse model for human melanoma - PubMed
This unit details protocols for in vivo models of subcutaneous growth and pulmonary metastases of B16 melanoma. Therapeutic approaches include the use of B16.GM-CSF and rVVmTRP-1 …
B16 melanoma - Wikipedia
B16 melanoma is a murine tumor cell line used for research as a model for human skin cancers. B16 cells are useful models for the study of metastasis and solid tumor formation, and were …
A novel immunogenic mouse model of melanoma for the …
2019年2月4日 · In vivo, the combination of BRAF and MEK inhibition significantly improved survival of YOVAL1.1-bearing C57BL/6 mice, with a median overall survival of 40 days on …
人鼠黑色素瘤B16荧光素酶标记肿瘤模型
B16黑色素瘤细胞(简称B16细胞)是来源于C57BL黑小鼠皮肤的自发性肿瘤。 裸鼠, 先天性胸腺缺陷的突变小鼠,是由于第Ⅶ连锁群(Linkage group)内裸体位点的等位基因发生纯合而形成的 …
Characterization of a B16-F10 melanoma model locally implanted …
The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study, B16-F10 cells are used to …
Transcriptome analysis of novel B16 melanoma metastatic variants ...
2025年1月16日 · In the present study we targeted the brain by injecting B16-F0 cells into the right carotid artery of syngeneic C57BL/6 mice, then reinjecting cells recovered from brain …
Syngeneic B16F10 Melanoma Causes Cachexia and Impaired …
Here, we investigated the B16F10 tumor-induced cachexia and its contribution to muscle strength and locomotor-like activity impairment. C57BL/6 mice were subcutaneously injected with 5 × …
B16 melanoma control by anti-PD-L1 requires CD8+ T cells and ... - PubMed
2021年7月3日 · When B16 tumor-bearing mice were treated with anti-PD-L1 in combination with Trp2 180-188 peptide vaccines, they displayed significantly more tumor control than either …
B Cells Are Required for Optimal CD4
2010年4月1日 · To test this hypothesis and quantify B cell contributions to T cell-mediated anti-tumor immune responses, mature B cells were depleted from wild type adult mice using CD20 …