Molecular Instruments - HCR™ Imaging
The HCR™ Platform is an innovative new method for generalized signal amplification borne out of the fields of synthetic biology and molecular programming. The mechanism is based on two …
HCR™ Amplification Technology | Molecular Instruments, Inc.
HCR™ Amplifiers leverage dynamic nanotechnology to enable small amplification components to first penetrate a biological sample without interacting and then autonomously grow bright …
Enhanced detection of expanded repeat mRNA foci with hybridization ...
Apr 23, 2021 · Repeat HCR (R-HCR) provided significantly higher sensitivity for detection of repeats and allowed accurate tracking of endogenous GGGGCC repeat RNAs in patient cells …
HCR™ IF + HCR™ RNA-FISHenables a unified approach to multiplexed, quantitative, high-resolution pro-tein immunofluorescence (IF) and RNA fluorescence in situ hybridization (RNA …
HyPR-seq: Single-cell quantification of chosen RNAs via …
Dec 12, 2020 · We began by adapting probes from the hybridization chain reaction (HCR) smFISH protocol (24, 25) for a sequencing-based readout. In HCR, two “initiator” probes …
Optimization and evaluation of fluorescence in situ hybridization …
Using multiple initiator-specific DNA hairpins tagged with different fluorophores (e.g., B1H1-AF647:B1H2-AF647; B2H1-AF488:B2H2-AF488), we were able to detect and directly …
HCR v3.0探针组，放大器和缓冲器-上海起发实验试剂有限公司
Sep 24, 2020 · HCR v3.0探针集，扩增子和缓冲液可在整个方案中实现多重定量RNA荧光原位杂交（RNA-FISH），RNA流式细胞仪和Northern印迹，并具有自动背景抑制功能。 探针组由分子 …
HCR probes Sequence (part of probe homologous to transcripts of interest) Amplifier ... lacZ B1H1, B1H2 Alexa Fluor 546 lacZ B1H1, B1H2 Alexa Fluor 488 prgB B2H1, B2H2 Alexa Fluor …
HCR反应探针H1和H2的设计有什么特别要求吗？ - X-MOL问答 - X …
Nov 27, 2024 · HCR反应探针H1和H2的设计有什么特别要求吗？ X-MOL学术平台旗下问答系统，汇集专家智慧，共同解决问题。 化学及相关领域的专业问题，包括实验原理、实验操作、 …
Applications of hybridization chain reaction optical detection ...
Jan 15, 2022 · Most HCR methods are linear reactions. The cross-opening cascade reaction of two kinetically trapped hairpin probes (H1 and H2) is initiated by one short DNA primer …