2023年8月9日 · 例如，b2m与肿瘤坏死因子（tnf）结合，可以增强tnf的效应，促进炎症反应和免疫细胞活化。 此外，B2M还与干扰素-γ（IFN-γ）等细胞因子相互作用，调节其在免疫应答和免 …

β2-Microglobulin（B2M）是一种小分子球蛋白，作为细胞表面人类淋巴细胞抗原（HLA）的β链（轻链）部分，在生物体内发挥着多重关键作用。 B2M由淋巴细胞、血小板、多形核白细胞 …

2021年3月3日 · We confirmed that B2M played a critical role in tumor progression, patient prognosis and immunotherapy of gliomas. Gliomas, originating from the supporting glial cells …

B2M and sIL-2R are biological markers of adjuvant IFN-α2b treatment. Low TNF-α levels are negatively associated with relapse-free survival. Conversely, high TNF-α levels are correlated …

2019年7月25日 · Selective inactivation of TNF signaling lowered melanoma and lung cancer thresholds to low TNF levels, thereby increasing tumor susceptibility to T cell attack and …

Here, B2M promoted CD80 expression and increased TNF-α, IL-6, and IL-8 production, but decreased CD163 levels. A previous study reported B2M-mediated TNF-α production in the …

2024年10月21日 · Here we show that a β2-microglobulin super-enhancer (B2M-SE) that is responsive to interferon-γ is a critical regulator of the expression of HLA-I on mesenchymal …

We measured tumor necrosis factor (TNF alpha), interleukin-1 (IL1-B), and beta-2 microglobulin (B2M) levels in 10 chronic hemodialysis patients before and during dialysis with six different …

2010年5月9日 · Combining baseline levels of TNF-α, B2M and sIL-2R has a predictive value for relapse of 82.9%. These results may help to identify patients at risk of relapse or, conversely, …

MCE提供FCRN-B2M 蛋白, Human (HEK293, His)，FCGRT 是一种 IgG Fc 受体。 Fc 受体表达受促炎细胞因子 TNF 上调，IFN-γ 下调。 FCGRT 在调节 IgG 和血清白蛋白转换中发挥作用。