2023年5月23日 · Each vial of TheraCys contains 81 mg of freeze-dried BCG. The freeze-dried BCG does not contain any preservative. One dose of TheraCys consists of one 81mg vial of freeze-dried BCG reconstituted and diluted in 50 mL sterile, preservative-free saline .

2024年4月4日 · BCG, when used intravesicularly for treatment of bladder carcinoma in situ, is thought to cause a local, chronic inflammatory response involving macrophage and leukocyte infiltration of the bladder. BCG (intravesical) is active immunotherapy which stimulates the host's immune mechanism to reject the tumor. Use: Labeled Indications

Intravesical bacillus Calmette–Guerin (BCG) instillation is widely used as an adjuvant therapy after transurethral resection of bladder tumor (TURBT) in patients with intermediate- and high-risk nonmuscle invasive bladder cancer (NMIBC). However, the effective dose, duration, and strain of BCG have not yet been clearly determined.

2018年8月19日 · Trans-urethral resection of the bladder (TURB) followed by adjuvant intravesical instillation with bacillus Calmette-Guérin (BCG) is the most effective conservative therapy for the treatment of high-risk non-muscle-invasive bladder cancer (NMIBC) (1 - 3).

• The patients were randomized into three treatment groups: a maintenance group (BCG, 81 mg, intravesically instilled once weekly for 6 weeks as induction therapy, followed by three once-weekly instillations at 3, 6, 12 and 18 months after initiation of the induction therapy), a non-maintenance group (BCG, 81 mg, intravesically instilled once ...

Another study by the same group on 155 patients with high-risk NMIBC treated with two different doses of BCG (81 and 27 mg of Connaught strain) showed that a one-third dose of BCG was as effective as the standard dose against progression and recurrence in patients with high-risk stage T1G3 and Tis superficial TCC. There was disease recurrence ...

2024年4月26日 · Detailed Bcg dosage information for adults and children. Includes dosages for Tuberculosis - Prophylaxis and Urinary Tumor; plus renal, liver and dialysis adjustments.

2024年10月29日 · TICE® BCG is indicated for: the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder - the prophylaxis of primary or recurrent stage Ta and/or T1 papillary tumors following ...

Meta-analysis of 2175 patients, 81 mg BCG was found to be superior to 27 mg in reducing tumour recurrences (RR 0.86; 95% CI 0.77-0.96, I2 = 0% and p=0.008).

In this study, we evaluated low dose intravesical bacillus Calmette-Guerin (BCG) therapy following transurethral resection (TUR) in 80 patients with superficial bladder cancer. The patients were divided into two groups. Of the Connaught BCG strain 81 mg was given to …