Restoring mono-ovulation is the ultimate goal of ovulation induction and most women do respond to ovulation inducing agents causing their Follicle-stimulating hormone (FSH) levels to rise. Familial clustering and the results from twin studies strongly support an …

促卵泡激素受体（英語：follicle-stimulating hormone receptor， FSH receptor， FSHR）是一种在 卵巢 、 子宫 和 睾丸 中发现的 G蛋白偶联受体 （GPCR），其激活是在繁殖期间的荷尔蒙运作所需的。 FSHR 基因位于人的 2號染色體 上p21区，长约2080个 核苷酸 [1]。 馬丁·羅德貝爾 与 艾爾佛列·古曼·吉爾曼 因发现G蛋白系统而获得1994年的 诺贝尔生理学或医学奖。 ^ Simoni M, Gromoll J, Nieschlag E.

2023年1月31日 · Follicle stimulating hormone (FSH) is an essential glycoprotein hormone for human reproduction, which functions are mediated by a G protein-coupled receptor, FSHR....

促卵泡激素（follicle-stimulating hormone，FSH）是由垂体分泌的一种糖蛋白激素，能够作用于性腺（睾丸或卵巢）组织特定靶细胞上的卵泡刺激素受体（FSHR），从而调控卵泡的成熟和排卵，以及诱导精子的发生。

The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). Its activation is necessary for the hormonal functioning of FSH. FSHRs are found in the ovary, testis, and uterus.

2025年2月8日 · Gene target information for FSHR - follicle stimulating hormone receptor (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

In this review, we describe the most important structural features of the FSHR intimately involved in regulation of FSHR function, including trafficking, dimerization, and oligomerization, ligand binding, agonist-stimulated activation, and signal transduction.

Follicle stimulating hormone (FSH) has effects on oogenesis and follicle development. Several polymorphisms of FSH receptor (FSHR) are related to primary amenorrhea, hypoplastic ovary, and high serum levels of FSH. Thus, an increase in FSH level leads to follicle maturation and proliferation of granulosa cells.

2018年1月1日 · Upon activation, FSHR activates a number of signal transduction pathways mediated by PKA, PKB, and MAPKs through activating various FSHR associated proteins such as G proteins, β-arrestins, and APPL1, which results in cellular proliferation and differentiation as well as desensitization/internalization/recycling of FSHR.

促卵泡激素（follicle-stimulating hormone，FSH）是由垂体分泌的一种糖蛋白激素，能够作用于性腺（睾丸或卵巢）组织特定靶细胞上的卵泡刺激素受体（FSHR），从而调控卵泡的成熟和排卵，以及诱导精子的发生。 FSH-FSHR信号稳态是人体生殖系统最重要的调控枢纽。