2003年6月20日 · The expressed BKV VP1 protein was self-assembled into virus-like particles (BK-VLPs) with two different sizes (50 and 26 nm in diameter), which migrated into four different bands in CsCl gradient with buoyant densities of 1.29, 1.30, 1.33, and 1.35 g/cm 3.

2011年11月1日 · The polyomavirus, BK virus (BKV) infects the majority of humans early in life, establishing persistent asymptomatic infections in immunocompetent individuals. The small size and non-redundant nature of the viral genome presents a …

2025年1月17日 · BKV is a ubiquitous virus belonging to the Polyomaviridae family. Virions are non-enveloped and typically between 40 and 45 nm in diameter. The genome of BKV is circular double-stranded DNA (dsDNA) of approximately 5.3 kilobases (1).

BKV is a small non-enveloped, circular doubled-stranded DNA virus with a genome size of approximately 5kb (kilobases) [2, 5]. BKV infection is ubiquitous with subclinical infections of 80–90% in the general population worldwide, but is often associated with pathology in immunocompromised individuals [6, 7, 8, 9].

2020年11月1日 · BKV genome is ∼5 kb in length and replicates bidirectionally from a unique origin within the noncoding control region (NCCR; also called transcriptional control region [TCR]).

BK virus (BKV) is a circular, double-stranded DNA virus with an approximately 5 kilobase-size genome in the polyomavirus family, of which 13 members of the family are known, including the JC virus (JCV) and SV40. BKV shares about 75% of its DNA sequence with JCV.

2018年6月14日 · The BK Virus (BKV) genome is a double-stranded, circular DNA molecule with genetic organization similar to other polyomaviruses, and high homology to JC Virus (JCV) and SV40. The archetypal form of BKV noncoding regulatory region (NCRR) is the infectious form of BKV that replicates in the urothelium and is excreted in the urine.

Within the genome of human polyomavirus BK (BKV), there exists a noncoding regulatory region toward the late region side of the origin of DNA replication. In most BKV strains isolated by viral culture, this regulatory region contains tandem repeats varying in …

2008年9月9日 · In infected tubular cells the early and late phases of infection could be distinguished according to expression of large T-antigen or VP-1. The early phase revealed almost normal nuclear proportions, whereas in later phases nuclear size increased about 2 …

2018年7月26日 · We study the global gene expression profiles of BKV viremia and nephropathy patients using microarrays in order to better understand the immunologic response to polyomavirus BK (BKV). BKV has become increasingly prevalent since the introduction of more potent immunosuppressive agents.