2021年6月14日 · Here, we report a biocompatible and biodegradable protein-based adhesive with high adhesion strengths. The maximum strength reaches 16.5 ± 2.2 MPa on hard substrates, which is comparable to that...

2012年8月12日 · BMO is built out of ¼” MDF (Medium Density Fiberboard). MDF is easy to glue, shape and cut, plus it seals very easily and can be coated to look like metal.

Cardboard BMO: Ever see a super cool cardboard sculpture and wonder to yourself “how the heck did they do this?!” well wonder no more! I’ve created an instructable that introduces the world of cardboard sculpture, cardboard crafts are an amazingly fun and cheap wa…

2022年6月21日 · Molecular glues are small molecules that interact with a variety of target proteins that are difficult to predict, exhibiting distinct biological activities by inducing and enhancing the interaction of two proteins that otherwise do not show an intrinsic affinity for each other.

2023年7月12日 · We first classify current FDA-approved molecular glues to facilitate the selection of discovery methods. We then survey two broad discovery method strategies, where we highlight the importance of factors such as experimental conditions, software packages, and genetic tools for …

2024年2月13日 · Bristol Myers Squibb is offering Roivant-backed VantAI up to $674 million biobucks in a new partnership aimed at designing molecular glues as small-molecule therapeutics.

Carefully cut out buttons from felt for BMO’s front panel and glue them in the configuration shown below.

Small molecule molecular glues can nucleate protein complexes and rewire interactomes. Molecular glues are widely used as probes for understanding functional proximity at a systems level, and the potential to instigate event-driven pharmacology has …

Watch video to learn about the science behind protein degradation and ongoing research that harnesses the power of this natural process with the hope of finding new treatments at Bristol Myers Squibb.

2024年4月16日 · Molecular glues offer exciting opportunities for targeted protein degradation and new ways to reach some of the estimated 85% of undruggable targets in the proteome. In this blog, we take stock of progress, look at what’s in store for drug development, and give examples of ways microplate readers can help advance research into molecular glues.