2017年5月1日 · Highly efficient organic nonlinear optical BNA compound was successfully synthesized using modified synthesis process which gave the excellent outcome product yield of about 70–75%. This modified synthesis method is found to be more suitable for the preparation of high pure BNA compound than the other method reported earlier.

A bridged nucleic acid (BNA) is a modified RNA nucleotide. They are sometimes also referred to as constrained or inaccessible RNA molecules. BNA monomers can contain a five-membered, six-membered or even a seven-membered bridged structure with a "fixed" C 3 ' …

所合成的bna化合物通过使用石油醚的低压硅胶通过柱色谱法（cc）分离，并通过薄层色谱法（tlc）确认分离出的所得产物的纯度。 进一步地，该材料在甲醇中至少重结晶四次，并且高度纯化的BNA通过室温下的缓慢蒸发法，用于从具有选定溶剂的溶液中生长单晶。

2023年12月18日 · BNA, the subject compound, the exothermic and endothermic nature was characterised by TG analyses, differential scanning calorimeter (DSC), functional studies by infrared (IR) spectra, NMR spectral and optical transmission studies.

2008年10月15日 · To optimize the nuclease resistance and hybridizing properties of 2′,4′-BNA, we aimed to develop a bridged nucleic acid (BNA) with a N3′→P5′ phosphoramidite linkage, 3′-amino-2′,4′-BNA (Fig. 1).

将2-甲基-4-硝基苯胺(na)转化为原料n-苄基-2-甲基-4-硝基苯胺(bna)，并通过重量分析计算bna在各种有机溶剂中的溶解度。 BNA 的溶解度和晶体结构使其成为低温溶液生长方法的优异溶剂，该方法用于创建通过单晶分析研究的具有斜方结构的 BNA 单晶。

2020年9月17日 · Synthesis of the organic nonlinear optical compound N-benzyl-2-methyl-4-nitroaniline (BNA) was carried out in a newer chemical environment using the mixture of benzyl chloride and 2-methl-4-nitroaniline by a preferred laboratory synthesis process. The synthesized BNA compound was separated by column

Bridged nucleic acid 2',4'-BNANC (2'-O,4'-aminoethylene bridged nucleic acid) 是一种含有N-O联接的六元环结构的化合物。这种新型核酸类似物可以被合成并嵌入到寡核苷酸中。与之前几代的限制性核酸（PNA & LNA）相比，BNA寡核苷酸对其互补链

BNA, is 2’,4’-BNANC (2’-O,4’-C-aminomethylene bridged nucleic acid), containing a six-membered bridged structure with an N-O linkage[27]. Specifically, the new generation 2’,4’-BNANC includes 2’,4’-BNANC[NH], 2’,4’-BNANC[NMe], and 2’,4’-BNANC[NBn] [27]; the structures of the BNA analogs are shown in figure 2. As

2017年5月1日 · Highly efficient organic nonlinear optical BNA compound was successfully synthesized using modified synthesis process which gave the excellent outcome product yield of about 70–75%. This modified synthesis method is found to be more suitable for the preparation of high pure BNA compound than the other method reported earlier.