Fluorescent fatty acid conjugates for live cell imaging of ... - Nature
2024年5月21日 · Here we report that the BODIPY-C12 fluorescent fatty acid probe stains functional and dysfunctional peroxisomes in live mammalian cells. We then go on to improve …
Water-Soluble BODIPY Photocages with Tunable Cellular …
2020年3月2日 · We present a simple, remote sulfonation solution to BODIPY photocages that imparts water solubility and provides control over cellular permeability while retaining their …
Influence of Simvastatin and Pravastatin on the Biophysical …
2024年8月24日 · Instead, simvastatin, within 5 min, significantly reduced the microviscosity of the plasma membranes in both A549 and HEK 293T cells, with intensity-weighted fluorescence …
FLIM of BODIPY-LD in LDs of HEK 293T cells (A), HEK 293T cells …
In contrast, LDs in human embryonic kidney cells (HEK 293T) possessed similar microviscosities in different cells, with intensity-weighted fluorescence lifetimes of BODIPY-LD ranging from 700...
Oxysterol binding to the extracellular domain of Smoothened in …
2013年7月7日 · BODIPY-cyclopamine and BODIPY-SANT1 binding assays. Various Smo proteins, tagged at their C termini with Cherry, were expressed in 293T cells either stably or by …
Metabolic determinants of cancer cell sensitivity to canonical ...
2020年8月10日 · Using functional genetic screens, we determined distinct metabolic genes that modulate cell proliferation in response to cystine limitation and GPX4 inhibition. In particular, …
Bimodal effects on lipid droplets induced in cancer and non …
In contrast, LDs in human embryonic kidney cells (HEK 293T) possessed similar microviscosities in different cells, with the intensity-weighted fluorescence lifetimes of BODIPY-LD ranging from …
Antiproliferative activity of meso -substituted BODIPY photocages ...
2023年11月5日 · The antiproliferative effect of BODIPY molecules was investigated against three human cancer cell lines MCF-7 (breast carcinoma), H460 (lung carcinoma), HCT116 (colon …
Synthesis and biological evaluation of nandrolone–bodipy conjugates ...
2015年5月1日 · The intracellular localization of nandrolone–bodipy 4 – 7 derivatives was examined in five cell lines: LNCaP, PC-3, MCF-7, HeLa, and HEK 293T cells. Fluorescence …
Molecular Engineering of Near-Infrared Light-Responsive BODIPY …
2019年7月9日 · The cytotoxicity was evaluated by testing the cell viability of human embryonic kidney 293T cell line and the 4T1 mammary carcinoma cell line cultured in different …
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